Negative pressure pulmonary edema: a case report

Abstract

Background The negative pressure pulmonary edema is rare clinical situation which caused mainly by upper airway obstruction. However except upper airway obstruction, there may be other pathophysiological disorders making patients more vulnerable to pulmonary edema. Based on these disorders, upper airway obstruction is the trigger to induce negative pressure pulmonary edema. Case presentation This case was a 5-year-old girl with tumor on saddle area, her hormones level were abnormal preoperatively, such as cortisol, adrenocorticotrophic hormone, free T4 and total T4. During the stage of induction, negative pressure pulmonary edema took place due to mild upper airway obstruction. And the instant chest Computer tomography proved diagnosis clue. After intensive care, most lung field of this girl recovered to normal within 48 h. Conclusion The patient with abnormal hormone levels is vulnerable to pulmonary edema, mild upper airway obstruction triggered negative pressure pulmonary. Thus pre-operation hormones supplement is as important as keeping upper airway unobstructed.

Negative Pressure Pulmonary Edema: A Case Report

“… 6 The clinical syndromes can usually improves after 12-24 hours. 7 But in our case, the symptoms were improved within 4 hours without any abnormalities. Patients with NPPE history should be kept in mind and prevention methods can be performed accordingly.…”

Imaging characteristics and mechanism of negative pressure pulmonary edema in children: three case reports

“…10 Type II NPPE usually occurs after relief of chronic airway obstruction, for example, after the operation of tonsillar hypertrophy, adenoid hypertrophy and upper respiratory tract tumours. 12,13 The incidence of NPPE is between 0.1 and 11%, 11,14,15 and it has been reported that the incidence of NPPE in China is as high as 9.6%. 16 The most common cause of NPPE in adults is the laryngospasm after extubation under general anaesthesia, with an incidence of 3% 11,12 ; but the cause of NPPE in children is different from that in adults, which is mainly due to airway obstruction.…”

“…Diagnosis of NPPE mainly depends on the history of foreign body inhalation, clinical manifestation and imaging features of pulmonary oedema. 12,13,15,17 Differential diagnosis between NPPE and the following diseases should be in consideration: cardiogenic pulmonary oedema caused by cardiac disease, low colloidal osmotic pulmonary oedema caused by hypoproteinemia, neurogenic pulmonary oedema caused by craniocerebral trauma or virus infection, allergic pulmonary oedema and aspiration pneumonia. None of the three children in this study had aforementioned diseases and were in good health before the airway foreign body obstruction.…”

Coexistence of Suprasellar Lesion and Pulmonary Congestion: Two Rare Cases and Literature Review

“…Along with hypothyriodism, hypocortisolism also occurred in the two cases. Patients with hypocortisolism might be suspected to be more vulnerable to lung leaking syndrome [14], because cortisol may decrease capillary permeability and ameliorate lung endothelial barrier dysfunction. Both mechanisms are strongly associated with mortality of septic shock [15,16].…”