Negative impact of deep venous thrombosis on chronic venous disease

Sánchez, Félix López; González‐Porras, José Ramón; Sánchez, Santiago Díaz; Roura, Josep Marinel·lo; Nevarez, Ignacio Sánchez; Carrasco, Eduardo; Rodríguez, J.R. Escudero; investigators, C-Vives Study

doi:10.1016/j.thromres.2013.01.011

Cited by 11 publications

(7 citation statements)

References 23 publications

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“…The risk factors deep vein reflux and DVT point out the role of CVD as the underlying pathology of the VLU. Two studies comparing patients with and without DVT support this pathway as they show significantly higher percentages of patients with VLUs in the DVT group . The involvement of CVD would also explain higher age as a risk factor since CVD deteriorates over time according to two large population studies .…”

Section: Discussionmentioning

confidence: 99%

A systematic review on risk factors in developing a first‐time Venous Leg Ulcer

Meulendijks

Vries

Dooren

et al. 2019

Acad Dermatol Venereol

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Venous Leg Ulcers (VLU) occur in about 1% of the Western population. A VLU takes 3–12 months to heal, it recurs often, and it has a negative impact on the quality of life. The risk factors for the development of a first VLU are not well‐understood and prevention of a first VLU therefore remains underappreciated. The aim of this study was to identify risk factors for developing a first VLU in adults (aged > 18 years) by searching the literature. We searched the Cochrane Library, Pubmed, Cinalh and Narcisto identify studies that investigated risk factors in developing a VLU. The last search was performed in January 2018. Two reviewers independently reviewed the abstracts and full‐text articles, and assessed the methodological quality of the included studies. Results of studies using duplex scanning, and comparing participants with and without VLUs were included in the qualitative analysis. Where possible a quantitative meta‐analysis was conducted. We found five studies that investigated the relation of several risk factors with VLU development. The methodological differences of the studies made it impossible to perform a quantitative analysis. The risk factors higher age (four studies), higher body mass index (four studies), low physical activity (four studies), arterial hypertension (four studies), deep vein reflux (three studies), deep venous thrombosis (three studies) and family history of VLU (three studies) were significantly associated with a VLU in the majority of the studies. To what extent they influence the development of a VLU remains unclear because of the limited number of studies that investigated the association of these risk factors with VLU development, and the heterogeneity of these studies. Further studies are needed to confirm the association of these risk factors with the development of a VLU and to explore overweight and low physical activity in more detail.

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Section: Discussionmentioning

confidence: 99%

A systematic review on risk factors in developing a first‐time Venous Leg Ulcer

Meulendijks

Vries

Dooren

et al. 2019

Acad Dermatol Venereol

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“…The questionnaire has been used in DVT studies but has not been through psychometric validation for this population. 31 , 32 During the assessment of the construct validity (demonstrating that the measure assesses its intended concept), the authors found that some of the items did not perform well. 33 This problem was amplified when implemented internationally.…”

Section: Resultsmentioning

confidence: 99%

“…These were eventually reduced to 20 items divided into four dimensions: physical, psychological, social, and pain. The questionnaire has been used in DVT studies but has not been through psychometric validation for this population 31,32 . During the assessment of the construct validity (demonstrating that the measure assesses its intended concept), the authors found that some of the items did not perform well 33 …”

Section: Resultsmentioning

confidence: 99%

Health‐related quality‐of‐life questionnaires for deep vein thrombosis and pulmonary embolism: A systematic review on questionnaire development and methodology

Asady

Ghanima

Jelsness-Jørgensen

et al. 2021

Research and Practice in Thrombosis and Haemostasis

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To improve the quality and accuracy of the patient‐reported outcome measures that assess health‐related quality of life (HRQoL), guidelines have been developed to standardize the development and validation process. Considering the increasing importance of HRQoL questionnaires in research, we set out to review the literature and evaluate whether existing questionnaires developed for deep vein thrombosis (DVT) and pulmonary embolism (PE) fulfill state‐of‐the‐art requirements. The literature search was conducted in March 2019 and updated in September 2020. Seven databases were searched. No time limit was set for the search to include all available questionnaires. The inclusion criteria were original publications describing the development of disease‐specific HRQoL questionnaires specific to DVT or PE in adults and available in English. The questionnaires were assessed to determine whether they fulfill the requirements in the latest guidelines. A total of 3826 references were identified. After the exclusion process, 15 papers were reviewed in full, of which 7 were included. Four questionnaires were developed for chronic venous disease, two were specific to DVT, and one was specific to PE. Most questionnaires we found in this review, fulfilled some but none fulfilled all recommendations in existing guidelines. Because the development of current available HRQoL questionnaires specific to DVT or PE do not fulfil all recommendations of existing guidelines, there is room for improvements within this field. Such improvements could likely enhance the quality associated with the use of these end points in clinical trials and practice.

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“… 18 What’s worse, compared to other patients with chronic vascular diseases (CVD), DVT patients seem to have poorer QoL. 19 , 20 However, a meta-analysis of patients with a history of DVT showed that QoL scores were comparable to population norms one year after an episode of DVT, 21 and a longitudinal study showed that QoL in patients following DVT improved over time. 22 Many studies have shown that PTS damages the QoL of patients following acute DVT.…”

Section: Introductionmentioning

confidence: 99%

Quality of Life Status and Influencing Factors Among Patients with Deep Vein Thrombosis

Huang

Liu

et al. 2022

PPA

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Objective The objective of the study was to describe the quality of life (QoL) status and investigate the influencing factors of QoL among patients with deep vein thrombosis (DVT). Methods A retrospective analysis at a single center was performed, and the clinical data of 161 patients with DVT admitted to West China Hospital of Sichuan University from June 2019 to June 2020 were collected with the Villalta scale, Hospital Anxiety and Depression Scale (HADS), and Chronic Venous Insufficiency Questionnaire (CIVIQ). The relationship between QoL and influencing factors, including characteristics, course of DVT, postthrombotic syndrome (PTS), psychological status, and behaviors, was analyzed by Student’s t -test, analysis of variance and multiple linear regression. Results A total of 161 patients who completed all the questionnaires between 2019 and 2020 were included, and 110 patients (68%) were male. The mean QoL score acquired by the CIVIQ scale was 74.18±8.44, and the results showed significant differences between patients of different ages, genders, behaviors and psychological statuses (P < 0.05). Multiple regression analysis showed that age (P = 0.024), negative mood (P < 0.001), CCI index (P < 0.001), PTS (P < 0.001) and regular exercise (P = 0.002) influenced the CIVIQ scale evaluation model, in which exercise regularly was a protective factor for QoL, and age, negative mood, CCI index and PTS were risk factors for QoL. Conclusion The QoL of DVT patients was impaired and associated with age, mood, CCI index and PTS. Regular exercise is beneficial for improving the quality of life of DVT patients.

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Negative impact of deep venous thrombosis on chronic venous disease

Cited by 11 publications

References 23 publications

A systematic review on risk factors in developing a first‐time Venous Leg Ulcer

A systematic review on risk factors in developing a first‐time Venous Leg Ulcer

Health‐related quality‐of‐life questionnaires for deep vein thrombosis and pulmonary embolism: A systematic review on questionnaire development and methodology

Quality of Life Status and Influencing Factors Among Patients with Deep Vein Thrombosis

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