Negative Appendectomy in Pregnant Women Is Associated with a Substantial Risk of Fetal Loss

McGory, Marcia L.; Zingmond, David S.; Tillou, Areti; Hiatt, Jonathan R.; Ko, Clifford Y.; Cryer, Henry

doi:10.1016/j.jamcollsurg.2007.05.025

Cited by 256 publications

(278 citation statements)

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“…14 McGory et al, in their study evaluating the impact of negative appen- dectomy on the subsequent fetal loss, found that there was no delay in the diagnosis of appendicitis in pregnant women. 4 Consistent with this data, after excluding women with negative appendicitis, we observed that 26.3% of the pregnant women had complex appendicitis, compared with 26.6% of non-pregnant women, indicating that there is no meaningful impact of delay in the diagnosis of appendicitis in pregnant women. Several studies in the literature have reported that the negative appendectomy rate is high in pregnant women and increases the risk of fetal loss and maternal mortality.…”

Section: Discussionsupporting

confidence: 86%

“…10 Our findings were not consistent with the literature. 4,10 In our study, we found that no statistically significant difference in time from first admission to operation was observed between the two groups (p=0.288). However, in contrast to the literature, the leukocyte count was higher in the non-pregnant group than in the pregnant patients with appendicitis.…”

Section: Discussioncontrasting

confidence: 54%

“…1 It is a well-established data that appendicitis during pregnancy is associated with increasing maternal--fetal mortality and morbidity including fetal loss, abortion, and preterm birth. 4 The correct diagnosis of appendicitis is challenging and reported to be often inaccurate during pregnancy. 8 Also, in several recent reports, it was shown that fetal and maternal complications are particularly high in cases with complex appendicitis.…”

Section: Discussionmentioning

confidence: 99%

“…3 It has been reported that any delay or misdiagnosis of acute appendicitis will eventually result in perforated or complex appendicitis with peritonitis, which is associated with high rates of early delivery, miscarriage, and fetal loss. 4 Despite the tendency to late diagnosis of acute appendicitis during pregnancy, it is reported up to 23% of negative appendectomy rate. 5 However, a recent study reported that higher rates of adverse obstetric outcomes were observed amongst pregnant women with negative appendectomy.…”

Section: Introductionmentioning

confidence: 99%

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The diagnosis of acute appendicitis in pregnant versus non-pregnant women: A comparative study

Aras

Karaman

Pekşen

et al. 2016

Rev. Assoc. Med. Bras.

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ArAs A et Al. 622rev assoC med bras 2016; 62(7):622-627 ORIGINAL ARTICLEThe diagnosis of acute appendicitis in pregnant versus non-pregnant women: A comparative study Objective: To investigate whether the diagnosis of acute appendicitis is affected by pregnancy or not. Method: A retrospective study with the analysis of the medical records of all women suspected of having appendicitis who underwent appendectomy at our hospital between June 2010 and March 2015 were reviewed. The patients were divided into two groups according to whether they were pregnant or not during the surgery: group I, pregnant women, and group II, non-pregnant women.Results: During the study period, 38 pregnant women and 169 non-pregnant women underwent appendectomy. The time from admission to the operation was not statistically different (2.17±1.47 days in group I vs. 1.98±1.66 day in group II; p=0.288). The pregnant group had longer hospital stay than the nonpregnant group (p=0.04). Ultrasonography (USG) was used as the first diagnostic modality in 36/38 patients in group I and 161/169 in group II. The non-visualized appendix on ultrasound was seen in 17 patients in group I and 51 patients in group II, which was not statistically different. Sensitivity and specificity of USG in diagnosis of acute appendicitis were 61.29 and 80.00% in group I, and 93.0 and 31.6% in group II, respectively. Conclusion: Although the diagnosis of appendicitis in pregnant women is not delayed, careful assessment of these patients suspected of having appendicitis should be encouraged when USG examination is normal or nondiagnostic.

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Section: Discussionsupporting

confidence: 86%

Section: Discussioncontrasting

confidence: 54%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

The diagnosis of acute appendicitis in pregnant versus non-pregnant women: A comparative study

Aras

Karaman

Pekşen

et al. 2016

Rev. Assoc. Med. Bras.

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“…McGory et al recently reported 454 cases of LA in pregnancy, by far the largest series documented to date [2]. A subsequent publication from our unit incorporated an additional 183 cases from the literature, yielding a systematic review of 637 cases of LA in pregnancy [3].…”

mentioning

confidence: 99%