2021
DOI: 10.4103/ijd.ijd_562_21
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Neem in Dermatology

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Cited by 9 publications
(14 citation statements)
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References 50 publications
(58 reference statements)
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“…In traditional medicinal systems of Africa, the fruits are used as laxative in Sudan and the Sahel; bark and leaves are used to treat wounds in central West Africa; bark is used to treat diarrhea in West African countries but leaves are used for the same purpose in East Africa [69] . A recent review has concluded from the available scientific literature that pulp, leaf, stem bark, and root extracts of the plant possess analgesic/antiinflammatory properties, which have been attributed to various factors like inhibition of a number of biological processes including cyclooxygenase-2 (COX-2) expression, inducible nitric oxide synthase (iNOS), 5-lipoxygenase biosynthesis, and tumor necrosis factor-α [75] . Fruit extract (aqueous) has been found to have analgesic activity properties as demonstrated in acetic acid-induced writhing, hot plate and formalin tests in rodent models.…”
Section: Resultsmentioning
confidence: 99%
See 1 more Smart Citation
“…In traditional medicinal systems of Africa, the fruits are used as laxative in Sudan and the Sahel; bark and leaves are used to treat wounds in central West Africa; bark is used to treat diarrhea in West African countries but leaves are used for the same purpose in East Africa [69] . A recent review has concluded from the available scientific literature that pulp, leaf, stem bark, and root extracts of the plant possess analgesic/antiinflammatory properties, which have been attributed to various factors like inhibition of a number of biological processes including cyclooxygenase-2 (COX-2) expression, inducible nitric oxide synthase (iNOS), 5-lipoxygenase biosynthesis, and tumor necrosis factor-α [75] . Fruit extract (aqueous) has been found to have analgesic activity properties as demonstrated in acetic acid-induced writhing, hot plate and formalin tests in rodent models.…”
Section: Resultsmentioning
confidence: 99%
“…Neem has reportedly more than 400 phytochemicals. The various skin or skin-related disorders that neem is used for both in conventional and traditional medicines include acne, eczema, impetigo, ulcers, pustules, snake and scorpion bites, chicken pox, measles, scaly scalp, psoriasis, pruritus, dermatophytosis, leprosy, pediculosis, and scabies [75] .…”
Section: Resultsmentioning
confidence: 99%
“…In recent years, there has been growing awareness surrounding the potential health risks and societal implications associated with the use of skin lightening products 5 . There is a strong need for further regulatory measures to be implemented to restrict the use of certain ingredients and promote safer alternatives 2 …”
Section: Introductionmentioning
confidence: 99%
“…2 However, these lightening agents come with a myriad of potential adverse effects, including cutaneous manifestations, predisposition to infections, and possible endocrinologic complications. 2 Another consideration of these cosmetic products is that they are typically used in the warmer climates and may increase percutaneous absorption in these settings, which can increase the likelihood and severity of adverse effects. 2 Hydroquinone, when used in high concentrations or for prolonged periods can lead to skin irritation, allergic reactions, and even permanent skin discoloration.…”
mentioning
confidence: 99%
“…
In recent years, social media platforms have become a popular medium for promoting beauty products, especially fairness products. 1,2 Fairness products refer to cosmetic products that are designed and marketed to lighten or brighten the skin tone. 1 They play a significant role in the personal care industry, catering to individuals who desire an even complexion or specific aesthetic appearance.
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mentioning
confidence: 99%