Needle Localization of Nonpalpable Breast Masses

Bigelow, Roger; Smith, R A; Goodman, Paul A.; Wilson, Gerald S.

doi:10.1001/archsurg.1985.01390290045007

Cited by 62 publications

(13 citation statements)

References 18 publications

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“…Its true incidence in the general population therefore cannot be reliably determined and is probably underestimated [8, 50, 54--56]. The results of 18 series [58][59][60][61][62][63][64][65][66][67][68][69] that reported 6609 nonpalpable breast biopsies (Table 2) show LCIS to comprise 2.2% (143 of 6609) of all biopsy specimens and 9.8% (143 of 1455) of all breast malignancies [31]. The results of 18 series [58][59][60][61][62][63][64][65][66][67][68][69] that reported 6609 nonpalpable breast biopsies (Table 2) show LCIS to comprise 2.2% (143 of 6609) of all biopsy specimens and 9.8% (143 of 1455) of all breast malignancies [31].…”

Section: Lcismentioning

confidence: 99%

Management of in situ and minimally invasive breast carcinoma

Frykberg

Bland

1994

World j. surg.

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In situ breast carcinoma represents an early localized stage in the transition to invasive breast carcinoma and has an especially favorable prognosis with appropriate management. The widespread use of mammography has contributed to its increased rate of diagnosis. The two histologic forms of this entity have distinct pathologic and biologic characteristics, with different therapeutic implications. Lobular carcinoma in situ is considered a marker of increased risk for subsequent invasive carcinoma and is most commonly managed by nonoperative surveillance. Ductal carcinoma in situ behaves more as a true anatomic precursor of invasive disease and has the same therapeutic options as invasive breast carcinoma. Minimally invasive breast carcinoma should be considered a fundamentally different entity, primarily because of its potential for systemic metastasis that in situ lesions do not theoretically have. There are still many outstanding issues and dilemmas to be resolved by scientific investigation before the intriguing potential of these early forms of breast malignancy are fully understood.

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Section: Lcismentioning

confidence: 99%

Management of in situ and minimally invasive breast carcinoma

Frykberg

Bland

1994

World j. surg.

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“…On the other hand, it is important to obtain a wide tumor-free resection margin if the lesion turns out to be malignant on histopathology. Preoperative needle localization offers an opportunity to make a rapid and accurate excision with minimal trauma and the least tissue damage 7–9. The cosmetic results assume great importance, considering that about 69% of these lesions are benign 10.…”

Section: Introductionmentioning

confidence: 99%

Usefulness of hook wire localization biopsy under imaging guidance for nonpalpable breast lesions detected radiologically

Masroor¹,

Afzal²,

Shafqat³

et al. 2012

IJWH

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BackgroundThe purpose of this study was to evaluate the usefulness of hook wire localization biopsy under imaging guidance for nonpalpable breast lesions detected radiologically.MethodsThis was a descriptive study conducted at the Department of Radiology, Aga Khan University Hospital, Karachi. All patients undergoing needle localization biopsy of a nonpalpable breast lesion under mammographic or ultrasound guidance between January 2009 to December 2010 were included in the study. Patients with incomplete medical records were excluded. All patients’ mammograms or ultrasound were categorized using BI-RADS® assessment categories. The percentages of benign and malignant lesions were determined by pathological examination of surgically removed specimens. A correlation was sought between preoperative imaging assessment and the final diagnosis. The complications associated with the procedure were also recorded.ResultsA total of 151 biopsies were carried out, of which 80 were performed under mammographic guidance and 71 were performed under ultrasound guidance. The mean age of the patients was 51.89 years. The overall malignancy rate was 25.16%. Of 93 cases reported radiologically as malignant, 60 turned out to be malignant, and of the 58 cases reported as benign on imaging, three proved to be malignant on histopathology. The sensitivity of imaging findings was 95% and the specificity was 62%. The malignancy rate was 5% for benign lesions and 64% for malignant lesions, respectively. There were no complications related to wire localization, and only two patients had minor complications following surgical excision, giving a complication rate of 1.32%.ConclusionHook wire localization biopsy is a safe and effective procedure for definitive diagnosis of suspicious lesions on imaging, and is more helpful if the imaging findings are suspicious.

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“…Non-palpable tumors present a challenge for surgeons performing BCS, as palpability often locates the tumor in the breast. The most clinically accepted standard is image-guided single needle wire localization (2,3). Specifically, MR image-guided wire localizations are of significance due to the clinical value of MRI in breast tumor detection and characterization (4,5).…”

Section: Introductionmentioning

confidence: 99%

Toward MR‐guided high intensity focused ultrasound for presurgical localization: Focused ultrasound lesions in cadaveric breast tissue

Bitton

Kaye

Dirbas

et al. 2011

Magnetic Resonance Imaging

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Purpose To investigate MR-HIFU as a surgical guide for non-palpable breast tumors by assessing the palpability of MR-HIFU created lesions in ex vivo cadaveric breast tissue. Materials and Methods MR-HIFU ablations spaced 5mm apart were made in 18 locations using the ExAblate2000 system. Ablations formed a square perimeter in mixed adipose and fibroglandular tissue. Ablation was monitored using T1wFSE images. MR-ARFI was used to remotely palpate each ablation location, measuring tissue displacement before and after thermal sonications. Displacement profiles centered at each ablation spot were plotted for comparison. The cadaveric breast was manually palpated to assess stiffness of ablated lesions and dissected for gross examination. This study was repeated on three cadaveric breasts. Results MR-ARFI showed a collective post ablation reduction in peak displacement of 54.8% ([4.41 ± 1.48]μm pre, [1.99 ± 0.82]μm post), and shear wave velocity increase of 65.5%, ([10.69± 1.60] mm pre, [16.33± 3.10] mm post), suggesting tissue became stiffer after the ablation. Manual palpation and dissection of the breast showed increased palpability, a darkening of ablation perimeter, and individual ablations were visible in mixed adipose/fibroglandular tissue. Conclusion The results of this preliminary study show MR-HIFU has the ability to create palpable lesions in ex vivo cadaveric breast tissue, and may potentially be used to pre-operatively localize non-palpable breast tumors.

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Needle Localization of Nonpalpable Breast Masses

Cited by 62 publications

References 18 publications

Management of in situ and minimally invasive breast carcinoma

Management of in situ and minimally invasive breast carcinoma

Usefulness of hook wire localization biopsy under imaging guidance for nonpalpable breast lesions detected radiologically

Toward MR‐guided high intensity focused ultrasound for presurgical localization: Focused ultrasound lesions in cadaveric breast tissue

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