Needle detachment from the Sure-T® infusion set in two young children with diabetes mellitus (DM) treated with continuous subcutaneous insulin infusion (CSII) and unexplained hyperglycaemia

Massa, Guy; Gys, Inge; Eyndt, Anniek Op’t; Wauben, Karen; Vanoppen, Astrid

doi:10.1515/jpem-2014-0214

Cited by 6 publications

(9 citation statements)

References 4 publications

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“…These thin and no longer than 5–6 mm measuring needles may be hard to detect in the muscle and destruction of muscle tissue during surgery has to be expected. Complications and discomfort caused by the detached catheter material were not reported in literature . The animal testing performed by the catheter manufacturer showed no migration of needle fragments could be observed .…”

Section: Discussionmentioning

confidence: 89%

Needle detachment in a slim and physically active child with insulin pump treatment

et al. 2015

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Insulin pump therapy (CSII) is well established in pediatric patients with type 1 diabetes. In childhood diabetes, insulin pump treatment shows considerable advantages such as fewer injections, increased flexibility, fewer hypoglycemic events and lower HbA1c levels. Side effects such as catheter obstruction, technical pump failure, and dermatological complications have been observed, but are rarely reported. The reported patient is a physically very active and slim 10-year-old boy with reduced subcutaneous fatty tissue. After strong muscular activity an accidental rupture of the infusion set and needle detachment occurred in October 2013. X-ray and ultrasound imaging localized the needle in the musculus rectus femoris dexter. The needle was kept in situ and oral antibiotic treatment to prevent inflammatory reaction was prescribed. Repeated ultrasound measurements documented that the needles position had remained unchanged. Steel needle catheters (Sure-T infusion set, 6 mm) positioned in a thin layer of subcutaneous fat tissue of the thigh, combined with intense sports activity can result in a needle rupture and penetration into the muscle. Careful monitoring provides an alternative to surgery and lowers the risk of muscular necrosis. Because of differences in the distribution of subcutaneous fat tissue, an individualized catheter selection is necessary in pump treatment for children and adolescents, requiring a variety of different catheter sets.

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Section: Discussionmentioning

confidence: 89%

Needle detachment in a slim and physically active child with insulin pump treatment

et al. 2015

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“…This patient used a single syringe for many injections over 3-4 days before discarding it; this practice should be absolutely avoided for the risk of infection and breakage. Massa et al described the detachment of needles from insulin continuous subcutaneous infusion set in two pediatric patients, with impossibility to remove them in one of two cases despite a long surgical intervention [4]. Moreover, there have been several reports of needle breakages during dental procedures, local anesthesia administration, among intravenous drug users, and in those who selfinject growth hormone.…”

Section: Discussionmentioning

confidence: 99%

Looking for a needle in a haystack: an older diabetic man with cheiroarthropathy loses an insulin pen needle in subcutaneous tissue

2020

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“…The conduit, whether cannula or needle, is subject to crimping, snagging, and dislodging as well. (18)(19)(20)(21)(22)(23)(24)(25) These make pump usage challenging for a normal, active life.…”

Section: Problems With Insulin Pumpsmentioning

confidence: 99%

Replacing Pumps with Light Controlled Insulin Delivery

Friedman

2019

Curr Diab Rep

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Purpose of Review-The aim of this review is to summarize the development of the photoactivated depot (PAD) approach for the minimally invasive and continuously variable delivery of insulin. Recent Findings-Using an insulin PAD, we have demonstrated that we can release native, bioactive insulin into diabetic animals in response to light signals from a small external LED light source. We have further shown that this released insulin retains bioactivity and reduces blood glucose. In addition, we have designed and constructed second generation materials that have high insulin densities, with the potential for multiple day delivery. Summary-The PAD approach for insulin therapy holds promise for addressing the pressing need for continuously variable delivery methods that do not rely on pumps, and their myriad associated problems.

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Needle detachment from the Sure-T® infusion set in two young children with diabetes mellitus (DM) treated with continuous subcutaneous insulin infusion (CSII) and unexplained hyperglycaemia

Abstract: We report on two young children with type 1 diabetes mellitus, treated by continuous subcutaneous insulin infusion, who developed severe hyperglycaemia and detachment of the needle from the insulin infusion set.

Cited by 6 publications

References 4 publications

Needle detachment in a slim and physically active child with insulin pump treatment

Needle detachment in a slim and physically active child with insulin pump treatment

Looking for a needle in a haystack: an older diabetic man with cheiroarthropathy loses an insulin pen needle in subcutaneous tissue

Replacing Pumps with Light Controlled Insulin Delivery

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