Necrotizing Soft Tissue Infections: APACHE II Score, Dissemination, and Survival

Abstract

By considering these two factors, more accurate outcome prediction may be possible, which may be useful for directing the management of patients with NSTIs.

Fournier's Gangrene: Review of 120 Patients and Predictors of Mortality

“…Median debridement count was three (1)(2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12). Majority of the debridements were performed under spinoepidural anesthesia; however, twenty-seven patients (22.5%) required general anesthesia.…”

“…Acute Physiology and Chronic Health Evaluation (APACHE) II scoring system is a commonly used method for predicting outcomes of critically ill patients with necrotizing soft tissue infection (NSTI). [12] Another well-defined method, which is also disease specific, is Fournier's Gangrene Severity Index (FGSI). [13] Uludag Fournier's Gangrene Severity Index (UFGSI) is a novel scoring system established by our department previously.…”

Are neutrophil-lymphocyte ratio and platelet-lymphocyte ratio as effective as Fournier's gangrene severity index for predicting the number of debridements in Fourner's gangrene?

“…[13][14][15]19] However, a study by Sallami et al reported the opposite results. [20] Yilmazlar et al [11] modified this scoring system and added two parameters: dissemination degree and age scores. In a study of 36 cases, the factors affecting the number of debridements in FG were investigated.…”

“…[6][7][8] There have been many efforts to find valuable prognostic criteria in the literature. [9][10][11] However, we did not find use of the neutrophil-lymphocyte ratio (NLR) and the platelet-lymphocyte ratio (PLR) in the English literature. We aimed to investigate the factors affecting the number of debridements, mortality rate, and cost, as well as the relationship between NLR, PLR, and prognosis.…”

Can we predict mortality in patients with necrotizing fasciitis using conventional scoring systems?

“…12.2016 validated as a predictor of 28-day mortality in patients who present to the emergency department (ED) with systemic inflammatory syndrome. [9] According to a Medline research, the APACHE II system was the severity score most often used for necrotizing fasciitis, [10][11][12][13] whereas the SOFA and SAPS systems was less often used to predict mortality in patients with necrotizing fasciitis, [14] with the MEDS scoring system never being used. Furthermore, no study has compared the scoring systems for predicting the mortality in patients with necrotizing fasciitis.…”