Necrotizing Soft-Tissue Infections: A Retrospective Review of Predictive Factors for Limb Loss

Park, Hee-Gon; Yang, Jong-Heon; Park, Byung-Hoon; Yi, Hyung-Suk

doi:10.4055/cios19166

Cited by 3 publications

(2 citation statements)

References 20 publications

(25 reference statements)

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“…Park H et al found that elevated CRP, creatinine, and glucose levels on initial blood tests and decreased Hb levels predicted a higher risk of amputation. 31 In addition to the above conventional indicators, procalcitonin (PCT) has become an indicator of infection that has received attention in recent years. PCT is released from the lungs and intestines and has a normal serum level of <0.01 μg/L.…”

Section: Laboratory Examinations and Scoring Systemsmentioning

confidence: 99%

“…In addition, patients with NF often develop renal insufficiency, presenting with blood urea nitrogen >18 mg/dL and serum creatinine >1.2 mg/dL. Park H et al found that elevated CRP, creatinine, and glucose levels on initial blood tests and decreased Hb levels predicted a higher risk of amputation 31 …”

Section: Diagnostic Criteria Based On Clinical Manifestation and Labo...mentioning

confidence: 99%

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Early diagnosis of necrotizing fasciitis: Imaging techniques and their combined application

Wei,

Huo,

Yang

et al. 2023

International Wound Journal

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Necrotizing fasciitis is a clinical, surgical emergency characterized by an insidious onset, rapid progression, and a high mortality rate. The disease's mortality rate has remained high for many years, mainly because of its atypical clinical presentation, which prevents many cases from being diagnosed early and accurately, resulting in patients who may die from uncontrollable septic shock and multi‐organ failure. But unfortunately, no diagnostic indicator can provide a certain early diagnosis of NF, and clinical judgement of NF is still based on the results of various ancillary tests combined with the patient's medical history, clinical manifestations, and the physician's experience. This review provides a brief overview of the epidemiological features of NF and then discusses the most important laboratory indicators and scoring systems currently employed to diagnose NF. Finally, the latest progress of several imaging techniques in the early diagnosis of NF and their combined application with other diagnostic indices are highlighted. We point out promising research directions based on an objective evaluation of the advantages and shortcomings of different methods, which provide a basis for further improving the early diagnosis of NF.

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Section: Laboratory Examinations and Scoring Systemsmentioning

confidence: 99%

Section: Diagnostic Criteria Based On Clinical Manifestation and Labo...mentioning

confidence: 99%

Early diagnosis of necrotizing fasciitis: Imaging techniques and their combined application

Wei,

Huo,

Yang

et al. 2023

International Wound Journal

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Prevalence and risk factors of wound complications after transtibial amputation in patients with diabetic foot

Park,

Eim,

Seo

2024

World J Diabetes

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BACKGROUND Diabetic foot (DMF) complications are common and are increasing in incidence. Risk factors related to wound complications are yet to be established after trans-tibial amputation under the diagnosis of DMF infection. AIM To analyze the prognosis and risk factors related to wound complications after transtibial amputation in patients with diabetes. METHODS This retrospective cohort study included seventy-two patients with DMF complications who underwent transtibial amputation between April 2014 and March 2023. The groups were categorized based on the occurrence of wound complications, and we compared demographic data between the complication group and the non-complication group to analyze risk factors. Moreover, a multivariate logistic regression analysis was performed to identify risk factors. RESULTS The average follow-up period was 36.2 months. Among the 72 cases, 31 (43.1%) had wound complications. Of these, 12 cases (16.7%) received further treatment, such as debridement, soft tissue stump revision, and re-amputation at the proximal level. In a group that required further management due to wound complications after transtibial amputation, the hemoglobin A1c (HbA1c) level was 9.32, while the other group that did not require any treatment had a 7.54 HbA1c level. The prevalence of a history of kidney transplantation with wound complications after transtibial amputation surgery in DMF patients was significantly greater than in cases without wound complications (P = 0.02). Other factors did not show significant differences. CONCLUSION Approximately 43.1% of the patients with transtibial amputation surgery experienced wound complications, and 16.7% required additional surgical treatment. High HbA1c levels and kidney transplant history are risk factors for postoperative wound complications.

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Postoperative necrotising fasciitis of the lower limb as an unexpected complication of vascular surgery procedure: Case report

Zogić¹,

Alihodzic²,

Toković³

et al. 2023

Scripta Medica

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Necrotising fasciitis is a rare and severe disease, acute infection, often life-threatening, characterised by rapid and progressive spread through the subcutaneous tissue and superficial fascia. It can occur on any part of the body, mostly affecting the perineum, limbs and abdominal wall. A 76-year-old male patient with the development of lower limb necrotising fasciitis after a vascular procedure femoral-popliteal bypass, performed due to chronic ischaemia is presented. Patient previously had several different vascular procedures on other blood vessels, with diabetes and cardiovascular disease as leading comorbidities. Treatment included urgent surgical necrotomy, with all measures of conservative treatment. During the treatment, there was no need for a new vascular procedure, arterial flow was preserved. It is necessary to constantly remind surgeons about this rare but life-threatening disease so that they can recognise it in time and adequately treat it.

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Necrotizing Soft-Tissue Infections: A Retrospective Review of Predictive Factors for Limb Loss

Cited by 3 publications

References 20 publications

Early diagnosis of necrotizing fasciitis: Imaging techniques and their combined application

Early diagnosis of necrotizing fasciitis: Imaging techniques and their combined application

Prevalence and risk factors of wound complications after transtibial amputation in patients with diabetic foot

Postoperative necrotising fasciitis of the lower limb as an unexpected complication of vascular surgery procedure: Case report

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