Necrotizing Sialometaplasia and Bulimia: A Case Report

Necrotizing sialometaplasia is a rare, benign, self-limiting inflammatory process, with most cases occurring in the palatal region. Although the pathophysiology of this condition remains unknown, it has generally been considered an ischemic reaction involving the minor salivary glands. Due to its clinical and histologic similarities to malignant salivary gland tumor, diagnostic biopsy is required. Careful monitoring is also recommended, and clinicians should provide sufficient information for pathologists to ensure the histologic diagnosis.

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“…Recently, studies have presented a few cases that occurred in relation to anorexia or bulimia [6,7].…”

Section: Discussionmentioning

confidence: 99%

Necrotizing Sialometaplasia: A Diagnostic Puzzle for Clinicians

Jeong

Park

2022

J Oral Med Pain

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“…The adrenaline in local anesthetic causes localized vasoconstriction and ischemia, which results in its formation. [ 2 ] Trauma from intubation procedure for general anesthesia also can result in necrotizing sialometaplasia, bulimia nervosa, an eating disorder with marked binge eating followed by purging [ 3 , 4 ]. Gatti A et al described a necrotizing sialometaplasia caused by excessive use of the nonsteroidal anti-inflammatory drug Flurbiprofen oral spray that contained alcohol six times once a day for five weeks for prevention of sore throat [ 5 ].…”

Section: Discussionmentioning

confidence: 99%

Necrotizing Sialometaplasia: A Diagnostic Challenge to Oral Physicians

Senthilnathan¹,

Mohan²,

Fenn³

et al. 2022

Cureus

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Necrotizing sialometaplasia is a rare, reactive, self-limiting disorder affecting a minor salivary gland that clinically mimics malignancy. Chronic smoking, alcohol use, trauma to the hard palate caused by local anesthetic injection due to the vasoconstrictive action of adrenaline in local anesthetic, topical application of nonsteroidal anti-inflammatory drugs like flurbiprofen spray used in bronchial asthma, oral intubation procedures for general anesthesia, ill-fitting dentures, bulimia nervosa, and minor salivary gland tumors are some of the contributing factors linked to its development. In this article, we discuss a rare, reactive, selflimiting condition affecting minor salivary gland, necrotizing sialometaplasia that occurred on the right posterolateral hard palate region in a 57-year-old male chronic smoker, diagnosed by oral medicine specialist by clinical findings and radiological evaluation by cone beam computed tomography that healed rapidly in three days by itself without any treatment, that prevented unwanted biopsy or surgery.

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“…It is generally more frequent in men in the fourth decade of life, with a reported average age of 49 years for men and 46 years for women [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

A diagnostic error of a necrotizing sialometaplasia: Case report

Gaouzi

Hallab

Taleb

2022

Annals of Medicine &Amp; Surgery

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Introduction Necrotizing sialometaplasia (NSM) is a benign, self-limiting, inflammatory disease of salivary glands, mainly involving the minor salivary glands in the palate. This lesion can mimic a malignant neoplasm, both clinically and histopathologically, manifesting as a submucosal swelling or as an ulcer of the palate. We illustrate our work with a case of necrotizing sialometaplasia misdiagnosed as carcinoma. Case presentation A 26 years old woman presented to dental treatment and consultation center of Rabat, for a rehabilitation of left palatal bone defect with an obturator prothesis. A postsurgical erythematous area was noted at the left palate during intraoral examination. After medical file study, we founded that she had a necrotizing sialometaplasia treated by maxillectomy of the left maxillary bone, and we realized that a diagnostic error was made leading to an aggressive treatment. Clinical discussion Necrotizing sialometaplasia can be misdiagnosed clinically and microscopically as a malignant neoplasm, resulting in inappropriate and aggressive treatment like the case presented. Conclusion The diagnosis of NSM is challenging, the role of histopathology and immunohistochemistry is of paramount importance.

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Necrotizing Sialometaplasia and Bulimia: A Case Report

Cited by 7 publications

References 28 publications

Necrotizing Sialometaplasia: A Diagnostic Puzzle for Clinicians

Necrotizing Sialometaplasia: A Diagnostic Puzzle for Clinicians

Necrotizing Sialometaplasia: A Diagnostic Challenge to Oral Physicians

A diagnostic error of a necrotizing sialometaplasia: Case report

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