Necrotizing Jejunitis: A Newly Discovered Disease in the Highlands of New Guinea

Resistance of the Breast-fed Infant to Gastroenteritis

“…The value of demand feeding might lie in the fact that undue periods of starvation and subsequent overfeeding that must be common in bottle-fed infants would be avoided. There is good evidence to suggest that starvation decreases the resistance of experimental animals to Gram-negative enteric infections, and overeating is known to play an essential part in the development of enterotoxaemia in sheep and possibly in man (Freter, 1955;Bullen and Scarisbrick, 1957;Formal et al, 1958;Murrell and Roth, 1963;Murrell et al, 1966). In-vivo experiments are at present being planned with a view to producing a breast-fed type of faecal flora and large bowel environment in bottle-fed babies.…”

Perspectives in Foodborne Illness

“…These events are sometimes followed after several days by acute intestinal syndromes in participants, varying from mild diarrheas to acute fulminating lethal diseases. 7 However, it is the fulminant lethal ones that really demand attention. Sharing of remnants of the pig feast over a few days to a few weeks with other clans and other villages, often the payback for previous debts or as part of celebrations like weddings, results in the geographic spread of these illnesses.…”

Neonatal necrotizing enterocolitis

“…The mechanism whereby excessive feeding may initiate events leading t O NEC remains speculative. Excessive intake has been associated with intestinal distension and altered peristalsis (46), which may result bacterial overgrowth favoring the development of NEC. Feeding results in increased blood flow and tissue 02 extraction in healthy neonatal piglets (47).…”