Necrotizing Fasciitis and Necrotizing Cellulitis Due to Group B Streptococcus

Report of 2 Fatal Cases of Adult Necrotizing Fasciitis and Toxic Shock Syndrome Caused byStreptococcus agalactiae

“…Nevertheless, necrotizing fasciitis caused by S. agalactiae, which is probably the most severe and fatal form of invasive streptococcal infection, has been only rarely described in the literature. To the best of our knowledge, only 9 cases have been previously reported in the English-language literature [11][12][13][14][15][16]; these involved 3 neonates, 1 boy (10 years old), and 5 adults (table 1). S. agalactiae caused necrotizing fasciitis in 3 children born prematurely [11,13] and 1 otherwise healthy child after operative treatment for a fracture [16].…”

“…To the best of our knowledge, only 9 cases have been previously reported in the English-language literature [11][12][13][14][15][16]; these involved 3 neonates, 1 boy (10 years old), and 5 adults (table 1). S. agalactiae caused necrotizing fasciitis in 3 children born prematurely [11,13] and 1 otherwise healthy child after operative treatment for a fracture [16]. Among reported adult infections, Sutton et al [15] described a case of necrotizing fasciitis that complicated an episiotomy , and Riefler et al [14] described another, involving a woman with diabetes mellitus.…”

Necrotizing fasciitis: a rare complication of hypospadias surgery in a child

“…Evaluation of the bacteriology of NF in childhood showed that 8% of infections were polymicrobial [10]. Wound cultures in our patient grew mixed aerobic and anaerobic bacteria.…”

Group B Streptococcal Infections

“…Although pulmonary infection caused by GBS is common, pleural involvement is rare, but it has been reported as a complication of early-onset [491] and late-onset [492] pneumonia. In addition to cellulitis and adenitis, GBS uncommonly can produce various unusual skin and soft tissue manifestations, including violaceous cellulitis [494], perineal cellulitis and septicemia after circumcision [495], scrotal ecchymosis as a sign of intraperitoneal hemorrhage [496], purpura fulminans [497,498], necrotizing fasciitis [499][500][501], impetigo neonatorum [502,503], omphalitis [421,504], scalp abscess secondary to fetal scalp electrode [505], abscess complicating cystic hygroma [506], retropharyngeal cellulitis [507,508], and breast abscess [509]. In affected infants, the onset of respiratory distress invariably occurs at or within 48 hours after birth, whereas the mean age at diagnosis of right-sided diaphragmatic hernia in the 40 reported cases is 11 days (range 4 to 91 days).…”