Necrotizing fasciitis

Chen, Leon L.; Fasolka, Brian; Treacy, Caitlin

doi:10.1097/01.nurse.0000694752.85118.62

Cited by 63 publications

(73 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…in practice and research. 15,16 Despite improvements in diagnosis and management, this rapidly progressive infection remains associated with high mortality rates of 10.9-76%. 2,3 The silver lining is that the mortality is directly proportional to the time to intervention.…”

mentioning

confidence: 99%

Modified Laboratory Risk Indicator for Necrotizing Fasciitis (m-LRINEC) Score System in Diagnosing Necrotizing Fasciitis: A Nested Case–Control Study

Wu¹,

Liu²,

Li³

et al. 2021

IDR

View full text Add to dashboard Cite

Aim This study aims to present a modified Laboratory Risk Indicator for Necrotizing Fasciitis (m-LRINEC) scoring system and to evaluate its ability in discriminating necrotizing fasciitis (NF) from other severe soft-tissue infections. Methods Patients with NF diagnosed by surgical findings in our institution between January 2014 and December 2020 were included as the case group, matched by controls with severe soft-tissue infections other than NF in a ratio of 2:1, based on demographics, calendar time and immunosuppressant status. Patients’ demographics, comorbidities and laboratory test results were extracted from medical records. Logistic regression analyses were used to determine the association with NF after adjustment for confounders, whereby m-LRINEC was developed. Receiver operating characteristics (ROC) curves and the area under the curve (AUC) were used to evaluate its discriminating ability. Results There were 177 patients included, 59 in the NF group and 118 in the non-NF group. We added comorbid diabetes and kidney disease to the original LRINEC scoring system, used high-sensitivity C-reactive protein (HCRP) to replace the CRP and redefined the cut-off values for the other four variables, to develop the m-LRINEC system. The cut-off value for m-LRINEC was 17 points, with corresponding sensitivity of 93.2% and specificity of 86.9%, and the AUC was 0.935 (95% CI 0.892 to 0.977; p <0.001). Conclusion The m-LRINEC scoring system shows a high sensitivity and specificity in discriminating NF from other severe soft-tissue infections. Patients with an m-LRINEC score of >17 points should have a high index of suspicion for the presence of NF. The validity of the m-LRINEC needs to be confirmed in studies with larger samples and better design.

show abstract

mentioning

confidence: 99%

Modified Laboratory Risk Indicator for Necrotizing Fasciitis (m-LRINEC) Score System in Diagnosing Necrotizing Fasciitis: A Nested Case–Control Study

Wu¹,

Liu²,

Li³

et al. 2021

IDR

View full text Add to dashboard Cite

show abstract

“…The role of HBOT and intravenous immunoglobulin G (IVIG) for the management of NF remains controversial. 9 In presented case, the first surgical intervention was performed more than 24 h after the onset of symptoms and during the treatment, it had to be repeated once more. HBOT was not applied due to cardiological and pulmonary contraindications.…”

Section: Discussionmentioning

confidence: 94%

“…In the United States NF affects about 0.4 in every 100,000 people per year 7 and an incidence goes up to 15 cases per 100,000 population in some areas of the world, [7][8][9] but due to underreporting, the number is certainly higher. According to Das et al and Bodansky et al, there is an increase in the frequency of NF in their countries.…”

Section: Discussionmentioning

confidence: 99%

Postoperative necrotising fasciitis of the lower limb as an unexpected complication of vascular surgery procedure: Case report

Zogić¹,

Alihodzic²,

Toković³

et al. 2023

Scripta Medica

View full text Add to dashboard Cite

Necrotising fasciitis is a rare and severe disease, acute infection, often life-threatening, characterised by rapid and progressive spread through the subcutaneous tissue and superficial fascia. It can occur on any part of the body, mostly affecting the perineum, limbs and abdominal wall. A 76-year-old male patient with the development of lower limb necrotising fasciitis after a vascular procedure femoral-popliteal bypass, performed due to chronic ischaemia is presented. Patient previously had several different vascular procedures on other blood vessels, with diabetes and cardiovascular disease as leading comorbidities. Treatment included urgent surgical necrotomy, with all measures of conservative treatment. During the treatment, there was no need for a new vascular procedure, arterial flow was preserved. It is necessary to constantly remind surgeons about this rare but life-threatening disease so that they can recognise it in time and adequately treat it.

show abstract

“…It occurs in patients of all ages but is more common in the elderly. It is distinguished by a severe, insidiously evolving soft-tissue infection of the fascia that moves along the fascial plane, with secondary necrosis of the subcutaneous tissues [ 46 ].…”

Section: Group 1: Dms Denoting Life-threatening Skin Diseases That Re...mentioning

confidence: 99%

An Overview of Clinical Manifestations of Dermatological Disorders in Intensive Care Units: What Should Intensivists Be Aware of?

2023

View full text Add to dashboard Cite

Acute skin failure is rarely the primary diagnosis that necessitates admission to an intensive care unit. Dermatological manifestations in critically ill patients, on the other hand, are relatively common and can be used to make a key diagnosis of an adverse drug reaction or an underlying systemic illness, or they may be caused by factors related to a prolonged stay or invasive procedures. In intensive care units, their classification is based on the aetiopathogenesis of the cutaneous lesion and, in the meantime, distinguishes critical patients. When evaluating dermatological manifestations, several factors must be considered: onset, morphology, distribution, and associated symptoms and signs. This review depicts dermatological signs in critical patients in order to lay out better recognition.

show abstract

Necrotizing fasciitis

Cited by 63 publications

References 16 publications

Modified Laboratory Risk Indicator for Necrotizing Fasciitis (m-LRINEC) Score System in Diagnosing Necrotizing Fasciitis: A Nested Case–Control Study

Modified Laboratory Risk Indicator for Necrotizing Fasciitis (m-LRINEC) Score System in Diagnosing Necrotizing Fasciitis: A Nested Case–Control Study

Postoperative necrotising fasciitis of the lower limb as an unexpected complication of vascular surgery procedure: Case report

An Overview of Clinical Manifestations of Dermatological Disorders in Intensive Care Units: What Should Intensivists Be Aware of?

Contact Info

Product

Resources

About