Necrotizing fasciitis

Asfar, Sami; Baraka, Ahmad; Juma, Talib; Marafie, Amin A.; Aladeen, T; Sayer, H Al

doi:10.1002/bjs.1800780722

Cited by 41 publications

(18 citation statements)

References 8 publications

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“…Median duration time of symptoms before presentation was statistically significant between patients who survived and those who died-3 [3][4][5][6][7][8][9][10][11][12][13] and 11 [7][8][9][10][11][12][13][14][15][16] days, respectively (P \ 0.001, Table 3). …”

Section: Resultsmentioning

confidence: 98%

The clinical features of Fournier’s gangrene and the predictivity of the Fournier’s Gangrene Severity Index on the outcomes

et al. 2008

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Fournier's gangrene (FG) is a rare, rapidly progressive, fulminant form of necrotizing fasciitis of the genital, perianal and perineal regions. Several factors have been reported to contribute to the clinical outcomes. The primary aims of this study were to examine the clinical features of patients with FG and evaluate the predictivity of the Fournier's Gangrene Severity Index (FGSI) score on the outcomes. We carried out a collective retrospective chart review of patients diagnosed and treated for FG in three reference centers between January 1995 and July 2007. Seventy-two patients with FG with were included to the study. Data were collected on medical history, symptoms, physical examination findings, admission and final laboratory tests, timing and extent of surgical debridement and antibiotic therapy. Perianal and perirectal abscess, scrotal abscess and urethral stenosis were the leading etiological factors. Diabetes mellitus was the predominant risk factor. Etiological factors and risk factors did not significantly contribute to survival or mortality, and duration of the symptoms was significantly longer in the non-survivor's group (P < 0.05). The FGSI scores were higher in the non-survivor's group. Regression analysis showed a FGSIS score of 10.5 as the cut-off to the outcome. Based on these results, we conclude that a patient's metabolic status and the extent of disease at presentation are the most important factors determining the prognosis of FG. The FGSI score may be considered as an objective and simple tool to predict the outcome in the patient with FG and should be used in further studies of FG patient series for comparison purposes.

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Section: Resultsmentioning

confidence: 98%

The clinical features of Fournier’s gangrene and the predictivity of the Fournier’s Gangrene Severity Index on the outcomes

et al. 2008

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“…Radical debridement of all in volved tissues should be performed immediately if fascial necrosis has been found. Wound inspection should be done 24 h after the first operation [5,[13][14][15]. We advo cate continuous lavage via Silastic drains in deep areas such as the ischiorectal region [16].…”

Section: Discussionmentioning

confidence: 99%

Necrotizing Fasciitis

et al. 1995

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“…Outro sintoma bastante característico é o início de dor local desproporcional aos achados. Há o surgimento de febre e toxemia sistêmica, que geralmente também são desproporcionais aos achado físicos 1 . Comumente a FN não ocorre antes do 3-5° dia de PO e os sintomas e achados locais podem confundir o clínico, sendo o diagnóstico geralmente tardio.…”

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“…Os agentes mais comumente encontrados são: Escherichia coli, Bacterioides spp., Streptococcus anaeróbios, Streptococcus faecalis e coliformes 1,10 . A FN monomicrobiana é principalmente causada por S. pyogenes e mais raramente por Clostridium perfringens, Staphylococcus aureus, Pseudomonas aeruginosa e Vibrio vulnificus 6 .…”

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