Necrotising herpetic retinopathies: a review and progressive outer retinal necrosis case report

Ittner, Erica A; Bhakhri, Raman; Newman, Tricia L.

doi:10.1111/cxo.12284

Cited by 16 publications

(9 citation statements)

References 28 publications

(220 reference statements)

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“…visual 1,6 . El cuadro clínico es similar, independiente de su etiología y afecta tanto a pacientes inmunocomprometidos o inmunocompetentes 1,6 .…”

Section: Discussionunclassified

“…visual 1,6 . El cuadro clínico es similar, independiente de su etiología y afecta tanto a pacientes inmunocomprometidos o inmunocompetentes 1,6 . Las causas predominantes corresponden al VHS y VVZ y su frecuencia relativa no depende de la edad 6 .…”

Section: Discussionunclassified

“…El cuadro clínico es similar, independiente de su etiología y afecta tanto a pacientes inmunocomprometidos o inmunocompetentes 1,6 . Las causas predominantes corresponden al VHS y VVZ y su frecuencia relativa no depende de la edad 6 . En nuestro paciente otras causas de panuveitis fueron razonablemente descartadas por la historia clínica y exámenes complementarios tales como toxoplasmosis, sífilis, tuberculosis, enfermedad por arañazo de gato, toxocariasis o enfermedades autoinmunes.…”

Section: Discussionunclassified

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Necrosis retiniana aguda por virus varicela zoster en un paciente inmunocompetente con seguimiento de la respuesta terapéutica mediante reacción de polimerasa en cadena

Fíca

Aceituno

Montecinos

et al. 2021

Rev. chil. infectol.

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“…visual 1,6 . El cuadro clínico es similar, independiente de su etiología y afecta tanto a pacientes inmunocomprometidos o inmunocompetentes 1,6 .…”

Section: Discussionunclassified

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Necrosis retiniana aguda por virus varicela zoster en un paciente inmunocompetente con seguimiento de la respuesta terapéutica mediante reacción de polimerasa en cadena

Fíca

Aceituno

Montecinos

et al. 2021

Rev. chil. infectol.

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“…The seventh patient showed quadrantally distributed white granular lesions without retinal hemorrhages and was misdiagnosed as PORN, which is also a kind of necrotizing herpetic retinopathies detected in immune-compromised patients [19]. CMVR and PORN might present confusing fundus changes, which could be difficult for inexperienced doctors, but they are different in the aetiological agent, treatment, and prognosis [20].…”

Section: Discussionmentioning

confidence: 99%

Retrospective analysis of misdiagnosis of cytomegalovirus retinitis

Du¹,

Huang²,

Chen³

et al. 2020

Preprint

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Background Initial misdiagnosis of cytomegalovirus retinitis (CMVR) may lead to irreversible loss of vision and systemic deterioration. We retrospectively reported some misdiagnosis related to CMVR. Methods The medical records of 92 consecutive patients diagnosed or misdiagnosed as CMVR were reviewed retrospectively at the ophthalmology department of Beijing youan hospital from July 2017 to October 2019. The primary outcome measure was to evaluate cases with CMVR who were initially misdiagnosed or who were misdiagnosed as CMVR. Results In 8 (8.7%) out of the 92 patients, the initial diagnosis was incorrect. The median age of the eight patients was 37.5 years (range 20-46 yeas). All (7/7, 100%) patients were male. Patients with CMVR were initially misdiagnosed as diabetic retinopathy (1/92,1.1%), branch retinal vein occlusion (1/92,1.1%), ischemic optic neuropathy (1/92,1.1%), Behcet′s disease (1/92,1.1%), iridocyclitis (2/92, 2.3%), and progressive outer retinal necrosis (1/92,1.1%). One patient with binocular renal retinopathy and chronic renal insufficiency was misdiagnosed as CMVR (1/92,1.1%). All patients presented binocular involvement (sixteen eyes), and two patients (four eyes) presented pan-retinal involvement. Fourteen eyes (14/16, 87.5%) had optic disc or macular area involved. One patient is blind, and two patients had a low vision when the diagnosis is finally clear. Five patients had systemic symptoms. Seven patients were finally diagnosed with AIDS showing an extremely low level of CD4 + T lymphocyte: median of 5 cells/ul (range 1-9 cells/ul). Conclusion The misdiagnosis of CMVR can occur in young male patients. The ophthalmologist should pay more attention to CMVR and systemic symptoms insulting to avoid deterioration of vision and delaying in the management of systemic conditions.

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“…75,104,114,128,191,241,244 There is minimal nongranulomatous anterior uveitis and vitri-tis. 191,241 Extensive multifocal necrotizing chorioretinitis begins at the posterior pole and spreads toward the peripheral retina.…”

Section: Viral Posterior Uveitismentioning

confidence: 99%

Viral posterior uveitis

Lee

Agarwal

Mahendradas

et al. 2017

Survey of Ophthalmology

103

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The causes of posterior uveitis can be divided into infectious, autoimmune, or masquerade syndromes. Viral infections, a significant cause of sight-threatening ocular diseases in the posterior segment, include human herpesviruses, measles, rubella, and arboviruses such as dengue, West Nile, and chikungunya virus. Viral posterior uveitis may occur as an isolated ocular disease in congenital or acquired infections or as part of a systemic viral illness. Many viruses remain latent in the infected host with a risk of reactivation that depends on various factors, including virulence and host immunity, age, and comorbidities. Although some viral illnesses are self-limiting and have a good visual prognosis, others, such as cytomegalovirus retinitis or acute retinal necrosis, may result in serious complications and profound vision loss. Since some of these infections may respond well to antiviral therapy, it is important to work up all cases of posterior uveitis to rule out an infectious etiology. We review the clinical features, diagnostic tools, treatment regimens, and long-term outcomes for each of these viral posterior uveitides.

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Necrotising herpetic retinopathies: a review and progressive outer retinal necrosis case report

Cited by 16 publications

References 28 publications

Necrosis retiniana aguda por virus varicela zoster en un paciente inmunocompetente con seguimiento de la respuesta terapéutica mediante reacción de polimerasa en cadena

Necrosis retiniana aguda por virus varicela zoster en un paciente inmunocompetente con seguimiento de la respuesta terapéutica mediante reacción de polimerasa en cadena

Retrospective analysis of misdiagnosis of cytomegalovirus retinitis

Viral posterior uveitis

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