Necrotising granulomatous lymphadenitis

Necrotizing granulomatous inflammation of the liver

“…The current case was finally diagnosed as NGI based on microscopic findings, and negative results of acid-fast bacilli smear after ZN stain and sputum culture. Because negative result of TB culture does not exclude the possibility of TB infection [1] , the current case still received anti-TB treatment in the follow-up period.…”

“…It usually occurs in the lung. The extrapulmonary sites commonly include lymph node, pleura, and joints, although any organ may be involved [1] . However, its causes still remained unexplained in nearly 20%-40% of cases [2] , [3] .…”

Inferring the diagnostic potential of 18F-FDG-PET/CT in post-renal transplantation from a unique case harboring multiple rare complications

“…Necrotizing granulomatous inflammation (NGI) is usually caused by tuberculosis, which usually occurs in the lung. The extrapulmonary sites commonly include lymph node, pleura, and joints, although any organ may be affected (36). Despite a complete histological evaluation with clinical, microbiological and serological correlation, nearly 20−40% of necrotizing granulomas remain undetermined (37).…”

Woman with necrotising granulomatous lymphadenitis: the key was in anamnesis and physical examination

“…However, a German study found that cat scratch diseases was present in 13.4% of the 454 patient with head and neck lymphadenopathy analysed, being reticular abscessed granuloma the most frequent pathological finding [7]. Diagnosis in the case of NGL can be challenging because the probability of tuberculosis is remarkable and the detection of bacilli may not be possible with conventional methods due to the low bacillary load in certain extrapulmonary territories, being necessary occasionally to confirm the diagnosis according to the response to anti-tuberculosis treatment [8,9]. Cat scratch disease is an infectious disease caused by B. henselae, a Gram-negative bacillus found in cats and fleas.…”