Necrotic cutaneous arachnidism in the U.K.

Sakka, S.; Howse, J.P.

doi:10.1111/j.1365-2133.1994.tb03398.x

Cited by 2 publications

(2 citation statements)

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“…The predominance of Gram-negative pathogens in our cohort can be interpreted by the inhabitance of hospital environments by these organisms which are known to harbor multidrug-resistance determinants adding to the complexity of management of COVID-19 cases [ 23 ]. Some studies reported lower incidence of coinfection because the study was designed to include co-infections in all COVID-19 patients, whereas our data were restricted to non-survivors [ 13 , 24 ]. It is difficult to accurately estimate coinfection rate in all COVID-19 cases due to the fact that not all patients are being tested serially for coinfection, particularly during the early phase of the COVID-19 pandemic due to pressure on the healthcare systems.…”

Section: Discussionmentioning

confidence: 99%

Bacterial and Fungal Coinfection in Critically Ill COVID-19 Cases and Predictive Role of Procalcitonin During the First Wave at an Academic Health Center

Alnimr

Alshahrani

Alwarthan

et al. 2022

J Epidemiol Glob Health

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Background Coinfection at various sites can complicate the clinical course of coronavirus disease of 2019 (COVID-19) patients leading to worse prognosis and increased mortality. We aimed to investigate the occurrence of coinfection in critically ill COVID-19 cases, and the predictive role of routinely tested biomarkers on admission for mortality. Methods This is a retrospective study of all SARS-CoV-2-infected cases, who were admitted to King Fahad Hospital of the University between March 2020 and December 2020. We reviewed the data in the electronic charts in the healthcare information management system including initial presentation, clinical course, radiological and laboratory findings and reported all significant microbiological cultures that indicated antimicrobial therapy. The mortality data were reviewed for severely ill patients who were admitted to critical care units. Results Of 1091 admitted patients, there were 70 fatalities (6.4%). 182 COVID-19 persons were admitted to the critical care service, of whom 114 patients (62.6%) survived. The in-hospital mortality was 13.4%. Coinfection was noted in 67/68 non-survivors, and Gram-negative pathogens (Enterobacterales, Pseudomonas aeruginosa, and Acinetobacter baumanni) represented more than 50% of the etiological agents. We noted that the serum procalcitonin on admission was higher for non-survivors (Median = 1.6 ng/mL ± 4.7) than in survivors (Median = 0.2 ng/mL ± 4.2) (p ≤ 0.05). Conclusion Coinfection is a serious complication for COVID-19 especially in the presence of co-morbidities. High levels of procalcitonin on admission may predict non-survival in critically ill cases in whom bacterial or fungal co-infection is likely.

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Section: Discussionmentioning

confidence: 99%

Bacterial and Fungal Coinfection in Critically Ill COVID-19 Cases and Predictive Role of Procalcitonin During the First Wave at an Academic Health Center

Alnimr

Alshahrani

Alwarthan

et al. 2022

J Epidemiol Glob Health

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“…There are only a few published cases of necrotic arachnidism with distinct identification of the culprit spider in Europe, and, worldwide, only a very small proportion of spiders have so far been identified to induce necrotic ulcers ( 2 , 5 , 6 ). Therapeutic strategies therefore remain speculative and empirical.…”

Section: Discussionmentioning

confidence: 99%