Necrosis of the Anterior Pituitary Following Parturition

Gotshalk, Henry C.; Tilden, I. L.

doi:10.1001/jama.1940.62810010001008

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1940

1979

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Cited by 8 publications

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“…In this setting, a sudden drop in blood pressure due to postpartum hemorrhage might allow the increased tissue pressure to cause collapse of the pituitary vasculature and ischemic necrosis. Gotshalk and Tilden described a patient who was found to have a segment of the anterior lobe of the pituitary protruding from the sella at autopsy; no necrosis was found in this area consistent with their hypothesis [17]. Meador and Worrell reported three patients with Sheehan's Syndrome in whom the sella turcica was significantly smaller than in normal controls [18].…”

Section: Resultsmentioning

confidence: 56%

Anterior Pituitary Function in Women with Postpartum Hemorrhage

Kayne¹,

Burrow

1979

Obstetrical & Gynecological Survey

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Thirteen asymptomatic women with postpartum blood loss of at least 500 cc were evaluated for anterior pituitary endocrine function. Insulin tolerance tests and TRH stimulation tests were done and determinations made for serum growth hormone, cortisol, thyrotropin, and prolactin. There was no laboratory evidence of pituitary dysfunction in this group of 13 patients. Subclinical hypopituitarism in women with previous postpartum hemorrhage would appear to be uncommon.

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Section: Resultsmentioning

confidence: 56%