Nebcin in the treatment of experimental Pseudomonas keratitis.

Belfort, Rubens; Smolin, Gilbert; Okumoto, Masao; Kim, H B

doi:10.1136/bjo.59.12.725

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Cited by 9 publications

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“…The comparative in vivo studies that have been done indicate that there is no notable difference between tobramycin and gentamicin against Enterobacteriaceae [11,15,16], and that tobramycin is somewhat more effective than gentamicin in treating infections caused by Pseudomonas [1,5,6,13,14], If this is confirmed by further in vivo studies, it will indicate that the PDM medium is not suitable for sensitivity testing of Enterobacteriaceae and Pseudomonas spp. against the two most commonly used aminoglycosides.…”

Section: Discussionmentioning

confidence: 96%

Comparative <i>in vitro </i>Activity of Tobramycin and Gentamicin on Three Different Media

Sandven¹,

Lassen²,

Solberg³

et al. 1980

Chemotherapy

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The minimal inhibitory concentration for tobramycin and gentamicin against 488 clinical isolates of Enterobacteriaceae, Staphylococcus aureus and Pseudomonas spp. were obtained on three different solid media. The results obtained on Antibiotic Sensitivity Medium AB Biodisk (PDM) were markedly different from the results obtained on Mueller-Hinton (MH) and Diagnostic Sensitivity Test Agar Oxoid (DST). It was shown that tobramycin was significantly disfavored relative to gentamicin by PDM agar compared to MH and DST agar.

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