Not only to reduce the candidates but also to maintain detection performance in multiple-input multiple-output (MIMO) detection, an adaptive overlapped cluster (AOC) scheme to balance detection error and computing cost is built for 4 × 4 and 8 × 8 MIMO-OFDM systems with up to 256 quadrature amplitude modulation (QAM). The constellations are partitioned into several clusters. A cluster with size decided by channel status is chosen for signal decoding. Different partition schemes are combined to minimize the numbers of clusters required to cover a candidate symbol as the pre-estimated signal falls at cluster edges, namely overlapped clustering. The simulations of a 4 × 4 MIMO OFDM with 64 QAM and 8 × 8 MIMO OFDM with 256 QAM hint that the AOC-based detection requires an additional 0.57 dB and 1.02 dB compared to maximum likelihood (ML). Compared with K-best sphere decoding (SD), it is reduced the computing complexity to 24.50% ∼ 56.25% in 4 × 4 MIMO OFDM and, 35.00% ∼ 56.25% in 8 × 8 MIMO OFDM. In addition, the proposed scheme is ported to a reconfigurable frequency-domain (FD) modem, which is designed and implemented via TSMC 45-nm technology, with multi-rate clocking and processing elements (PEs) upgrading for supporting the proposed MIMIO detection. The results show that the throughput is 1077.8 Mbps with 4 × 4 64-QAM modulations. INDEX TERMS Low complexity, MIMO detection, multi-rate clock, cluster, reconfigurable modem.