Near-Infrared Surface Plasmon Resonance Measurements of Ultrathin Films. 1. Angle Shift and SPR Imaging Experiments

Nelson, Bryce P.; Frutos, Anthony G.; Brockman, and Jennifer M.; Corn, Robert M.

doi:10.1021/ac990517x

Cited by 272 publications

(222 citation statements)

References 33 publications

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“…Angular dependent intensities of SPCECL (bottom). The upper panel shows the reflectivity of the gold film calculated using a gold dielectric constant of ε m = −10.5 + 1.49i and the software from [23,24] and http://corninfo.chem.wisc.edu Emission spectra of [Ru(bpy) 3 ] 2+ (top) and of SPCECL in acetonitrile (bottom).…”

Section: Discussionmentioning

confidence: 99%

First observation of surface plasmon-coupled electrochemiluminescence

Zhang

Gryczyński

Lakowicz

2004

Chemical Physics Letters

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Section: Discussionmentioning

confidence: 99%

First observation of surface plasmon-coupled electrochemiluminescence

Zhang

Gryczyński

Lakowicz

2004

Chemical Physics Letters

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“…Indeed, optical techniques of various types are emerging as an important tool for monitoring the dynamics of biomolecule interactions on a solid surface. For instance, imaging surface plasmon resonance spectroscopy (SPR), 23,24 imaging optical ellipsometry (OE), 25 and reflectometric interference spectroscopy (RIFS) 26 are 3 label-free optical techniques that in essence measure the same optical dielectric response of a thin film and thereby detect changes of physical or chemical properties of the thin film such as thickness and mass density during biochemical reactions. Compared with the above 3 methods, the OIRD technique is a more sensitive form of ellipsometry that measures the difference in reflectivity between the s-and p-polarized lights.…”

Section: Introductionmentioning

confidence: 99%

Characterization of monoclonal antibody's binding kinetics using oblique-incidence reflectivity difference approach

Liu

Zhang

Dai

et al. 2015

mAbs

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(2015) Characterization of monoclonal antibody's binding kinetics using oblique-incidence reflectivity difference approach, mAbs, 7:1, 110-119, DOI: 10.4161/19420862.2014.985919 To link to this article: https://doi.org/10. 4161/19420862.2014 Monoclonal antibodies (mAbs) against human proteins are the primary protein capture reagents for basic research, diagnosis, and molecular therapeutics. The 2 most important attributes of mAbs used in all of these applications are their specificity and avidity. While specificity of a mAb raised against a human protein can be readily defined based on its binding profile on a human proteome microarray, it has been a challenge to determine avidity values for mAbs in a high-throughput and cost-effective fashion. To undertake this challenge, we employed the oblique-incidence reflectivity difference (OIRD) platform to characterize mAbs in a protein microarray format. We first systematically determined the K on and K off values of 50 mAbs measured with the OIRD method and deduced the avidity values. Second, we established a multiplexed approach that simultaneously measured avidity values of a mixture of 9 monospecific mAbs that do not cross-react to the antigens. Third, we demonstrated that avidity values of a group of mAbs could be sequentially determined using a flow-cell device. Finally, we implemented a sequential competition assay that allowed us to bin multiple mAbs that recognize the same antigens. Our study demonstrated that OIRD offers a highthroughput and cost-effective platform for characterization of the binding kinetics of mAbs.

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“…It is apparent from the curves that the largest change in signal (of the three) occurs at the mid-range resonance wavelength of 770 nm. One common measure of the signal change due to absorptive particles used in previous reports [6,17] is the maximum change in reflectivity; with this measure, the signal change due to colloidal gold nanoparticles is approximately 30% at 650 nm, 49% at 770 nm, and 47% at 920 nm. An alternative measure, which depends on the difference curve across the investigated wavelength range and more completely describes the quantifiable difference in such signals, is the sum of the absolute value of the difference curve [5].…”

Section: Resultsmentioning

confidence: 99%

Dependence of the signal amplification potential of colloidal gold nanoparticles on resonance wavelength in surface plasmon resonance-based detection

Ramsey²,

Yager³

2007

Analytica Chimica Acta

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We demonstrate the resonance wavelength-dependent signal of colloidal gold nanoparticles adsorbed to a planar gold surface in surface plasmon resonance (SPR)-based detection. Experimental measurements of the SPR signal as a function of particle surface coverage are presented for three different resonance wavelengths. The SPR signal due to the colloidal gold nanoparticles varies across the resonance wavelengths of 650 nm, 770 nm, and 920 nm. The experimental SPR curves show good agreement with the results of a Lorentz absorbance model at the lower particle surface coverages investigated. The results demonstrate an almost 2-fold signal difference for a subset of the experimental conditions explored.

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Near-Infrared Surface Plasmon Resonance Measurements of Ultrathin Films. 1. Angle Shift and SPR Imaging Experiments

Cited by 272 publications

References 33 publications

First observation of surface plasmon-coupled electrochemiluminescence

First observation of surface plasmon-coupled electrochemiluminescence

Characterization of monoclonal antibody's binding kinetics using oblique-incidence reflectivity difference approach

Dependence of the signal amplification potential of colloidal gold nanoparticles on resonance wavelength in surface plasmon resonance-based detection

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