2014
DOI: 10.1016/j.arthro.2014.04.097
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Near Infrared Spectroscopy for Rapid Determination of Mankin Score Components: A Potential Tool for Quantitative Characterization of Articular Cartilage at Surgery

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Cited by 27 publications
(26 citation statements)
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“…The findings in this study are supported by results from earlier studies on articular cartilage, which consists of similar matrix components as meniscus, although the collagen types differ. The NIR region where correlation was optimized is also consistent with earlier studies on cartilage . It is worth noting at this stage that the present optical method is not proposed as a replacement for the reference techniques, but merely as a means of estimating the composition of meniscus during arthroscopy.…”
Section: Discussionsupporting
confidence: 90%
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“…The findings in this study are supported by results from earlier studies on articular cartilage, which consists of similar matrix components as meniscus, although the collagen types differ. The NIR region where correlation was optimized is also consistent with earlier studies on cartilage . It is worth noting at this stage that the present optical method is not proposed as a replacement for the reference techniques, but merely as a means of estimating the composition of meniscus during arthroscopy.…”
Section: Discussionsupporting
confidence: 90%
“…The proposed optical technique takes advantage of light interaction with meniscus matrix on a molecular level, and is sensitive to micro‐ and macroscopic changes in the tissue structure and composition . Thus, it could be useful for rapid tracking of changes in meniscus composition, resulting from either matrix degeneration or tissue recovery/regeneration in follow up procedures after repair surgeries.…”
Section: Discussionmentioning
confidence: 99%
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“…An excellent correlation between NIR spectra and Mankin score OA grading was achieved by using PLS regression (83). Further, different components of Mankin score were successfully predicted using separate PLS regression models (89).…”
Section: ¡1mentioning
confidence: 99%
“…1, 2, 10, 1215, 23, 38, 68, 126, 131, 137, 154, 155, 178 The specificity and sensitivity of spectroscopic methods make them a potentially attractive approach for evaluating cartilage development. Using FTIR, for example, images of the distribution of tissue components can be made with a resolution of 6.25 µm.…”
Section: Spectroscopic Methods (Table 10)mentioning
confidence: 99%