Near infrared spectroscopy: Experience on esophageal atresia infants

Conforti, Andrea; Giliberti, Paolo; Mondı̀, Vito; Valfrè, Laura; Sgrò, Stefania; Picardo, Sergio; Bagolan, Pietro; Dotta, Andrea

doi:10.1016/j.jpedsurg.2014.01.010

Cited by 27 publications

(25 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…We chose a threshold of 20 % based on previous studies in cardiac and intensive care patients. Reduction from baseline greater than 20 % during surgery or in the neonatal intensive care unit was associated with postoperative neurologic changes and neurodevelopmental impairment at 1 year of age [10, 14]. …”

Section: Discussionmentioning

confidence: 99%

“…In spite of that, during general surgery the central nervous system is seldom directly monitored. Previous studies which were performed in intensive care unit and during infant cardiac surgery report cerebral desaturation greater than 20 % from baseline or an absolute decrease below 50 % to be associated with postoperative neurologic changes and neurodevelopmental impairment at 1 year of age [10, 11]. Therefore the aim of the present study was to find out the frequency of cerebral desaturation events and to identify possible predictors of change in cerebral oxygen saturation during neonatal and infant general surgery.…”

Section: Introductionmentioning

confidence: 91%

“…The lowest (minimal) rSO 2 c value of every patient, when SpO 2 was ≥90 % for premature newborns and ≥94 % for term newborns and infants [13] was compared to baseline value (% change). The main outcome measure was rSO 2 c value drop-off 20 % or more from baseline [10]. Patients with at least one rSO 2 c value drop-off 20 % or more from baseline formed desaturation group.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Assessment of risk factors for cerebral oxygen desaturation during neonatal and infant general anesthesia: an observational, prospective study

et al. 2016

View full text Add to dashboard Cite

Background: Cerebral oxygen saturation (rSO 2 c) decrease from baseline greater than 20 % during infant cardiac surgery was associated with postoperative neurologic changes and neurodevelopmental impairment at 1 year of age. So far, there is no sufficient evidence to support the routine monitoring of rSO 2 c during general surgical procedures in children. We aimed to find out the frequency of cerebral desaturation 20 % or more from baseline and to identify possible predictors of change in cerebral oxygen saturation during neonatal and infant general surgery. Methods: Forty-four infants up to 3 months of age were recruited. Before induction of anesthesia, two pediatric cerebral sensors were placed bilaterally to the forehead region and monitoring of regional cerebral saturation of oxygen was started and continued throughout the surgery. Simultaneously, mean arterial blood pressure (MAP), pulse oximetry (SpO 2 ), heart rate (HR), endtidal CO 2 , expired fraction of sevoflurane and rectal temperature were recorded. The main outcome measure was rSO 2 c value drop-off ≥20 % from baseline. Mann-Whitney U-test, chi-squared test, simple and multiple linear regression models were used for statistical analysis.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 91%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Assessment of risk factors for cerebral oxygen desaturation during neonatal and infant general anesthesia: an observational, prospective study

et al. 2016

View full text Add to dashboard Cite

show abstract

“…If successful, we imagine that BOS could be an additional vital sign obtained on premature infants. Other pediatric surgical diseases such as esophageal atresia and diaphragmatic hernia that have been studied with NIRS [15,16] may also be characterized by differences in spectral reflectance.…”

Section: Discussionmentioning

confidence: 99%

Early detection of necrotizing enterocolitis using broadband optical spectroscopy

Goldstein¹,

Beaulieu²,

Niño³

et al. 2018

Journal of Pediatric Surgery

View full text Add to dashboard Cite

Purpose: The definitive diagnosis of necrotizing enterocolitis (NEC) is typically at an advanced stage, indicating the need for sensitive and noninvasive diagnostic modalities. Near infrared spectroscopy (NIRS) has been utilized to noninvasively measure intraabdominal tissue oxygenation and to diagnose NEC, but specificity is lacking, in part because sensors are limited to a narrow band of the electromagnetic spectrum. Here, we introduce the concept of broadband optical spectroscopy (BOS) as a noninvasive method to characterize NEC. Methods: NEC was induced in 7-day old mice by gavage feeding with formula supplemented with enteric bacteria plus hypoxia. Transabdominal spectroscopy was performed daily using a broad-spectrum halogen light source coupled with a spectroradiometer capable of detection from 400 to 1800 nm. Results: A feature extraction algorithm was developed based on the spectral waveforms from mice with NEC. When subsequently tested on cohorts of diseased and control mice by a blinded examiner, noninvasive BOS was able to detect disease with 100% specificity and sensitivity. Conclusions: We reveal that the use of BOS is able to accurately and noninvasively discriminate the presence of NEC in a mouse model, thus introducing a noninvasive early diagnostic modality for this devastating disease.

show abstract

“…During surgery, perioperative monitoring of brain and renal oxygenation was feasible with the use of NIRS (near infrared spectroscopy). This method may guide anesthetic conduction and postoperative care [9].…”

Section: Discussionmentioning

confidence: 99%

Lower esophageal banding in extremely low birth weight infants with esophageal atresia and tracheoesophageal fistula is a life saving practice followed by a successful delayed primary thoracoscopy reconstruction

Margain

Perez-Etchepare

Varlet

et al. 2015

Journal of Pediatric Surgery

View full text Add to dashboard Cite

Near infrared spectroscopy: Experience on esophageal atresia infants

Cited by 27 publications

References 13 publications

Assessment of risk factors for cerebral oxygen desaturation during neonatal and infant general anesthesia: an observational, prospective study

Assessment of risk factors for cerebral oxygen desaturation during neonatal and infant general anesthesia: an observational, prospective study

Early detection of necrotizing enterocolitis using broadband optical spectroscopy

Lower esophageal banding in extremely low birth weight infants with esophageal atresia and tracheoesophageal fistula is a life saving practice followed by a successful delayed primary thoracoscopy reconstruction

Contact Info

Product

Resources

About