Near infrared spectroscopic assessment of hemodynamic changes in the early post-burn period

Assessment of burn depth and burn wound healing potential

“…Some of these techniques could become clinically useful as technology improves but others, including the 'gold standard' of biopsy/histology, are never likely to attain clinical usefulness because they are restricted to single or multiple small areas and are not practical for mapping large areas of the wound. Near infrared spectroscopic (NIRS) techniques have been assessed experimentally by Sowa et al [59] and clinically by Cross et al [60] in 16 patients. These spectroscopic techniques provide information on oxygen saturation and total haemoglobin when used in point mode; relative differences in oxygenation were obtained when used in the imaging mode.…”

Quantitative assessment of graded burn wounds in a porcine model using spatial frequency domain imaging (SFDI) and laser speckle imaging (LSI)

“…Finally, both traditional diffuse reflectance spectroscopy (DRS) and imaging have been investigated within the context of burn wounds by various groups [16][17][18][19]. Visible and near infrared (NIR) polarized light is used to illuminate the tissue and the remitted cross-polarized light is captured with a camera or fiber to isolate subsurface features in tissue.…”

“…DRS at visible wavelengths has a limited penetration depth and is suited to assessment of superficial wounds [20]. NIR light has the benefit of enabling imaging several millimeters deep in tissue and has been applied to pre-clinical burn measurements [16,19]. However, in the absence of an appropriate accounting system that can separate and resolve changes that result from absorption and scattering, these techniques can suffer from inaccurate results that have limited the progression of the technology in the clinic.…”

Burn Depth Assessment in Thermal Skin Burns: Review

“…[45][46][47] Bu spektroskopik teknik nokta modunda kullanıldı-ğında oksijen satürasyonu ve total hemoglobin hakkında bilgi sağlar. Görüntüleme modunda ise oksijenasyondaki nisbi farklılığı ortaya koyar.…”