“…5,6 By contrast, near-infrared (NIR) light has the capability of low phototoxicity, deep tissue penetration, and minimal photodamage to biological species, which is very attractive in biosensing. 7,8 Since a NIR-driven PEC aptasensor based on the upconversion nanoparticles and a TiO 2 /CdTe heterostructure for the detection of cancer cells was first described in 2016, 9 different NIR-active materials have been explored for PEC sensing. 10,11 For example, Zheng et al used NaYF 4 :Yb,Tm upconversion nanophosphors as signal amplification probes to develop a competitive NIR PEC immunosorbent assay for the detection of okadaic acid.…”