Near-infrared autofluorescence imaging for colonic cancer detection

Near-infrared autofluorescence for the detection of parathyroid glands

“…Several groups have exploited this broadband signal to assist in the detection of a variety of pathologies ranging from cutaneous melanin in pigmented skin disorders to neoplastic breast tissue. [16][17][18][19] The tissue autofluorescence in these studies was attributed to fluorophores such as melanin and porphyrins but none of these studies documented peak fluorescence in the NIR region. [16][17][18][19] Intrinsic biological fluorophores are typically reported to exhibit peak fluorescence below 800 nm of the NIR region.…”

“…[16][17][18][19] The tissue autofluorescence in these studies was attributed to fluorophores such as melanin and porphyrins but none of these studies documented peak fluorescence in the NIR region. [16][17][18][19] Intrinsic biological fluorophores are typically reported to exhibit peak fluorescence below 800 nm of the NIR region. 12 However, this paper clearly demonstrates the consistent presence of autofluorescence with peak emission at 820 nm in parathyroid and thyroid tissues.…”