“…The level of the examined parameter at the minimal and maximal depths differs by 2.55 times (p<0.01) which is determined by the assessment of the deeper structures in the rats performing microwave profiling by the probe working at the depth of 5 mm. It can be also explained by the fact that each subsequent dielectric permittivity value includes the previous one together with the contribution made by the tissues located in the range from the previous to the current probing level [11,[19][20][21].…”
Section: Resultsmentioning
confidence: 99%
“…Near-field microwave probing was carried out using a system, designed in the Institute of Applied Physics of the Russian Academy of Sciences (Nizhny Novgorod, Russia), and specialized software interfacing the system and computer, and enabling the calculation of real part of dielectric permittivity [11,16]. Skin dielectric characteristics were assessed at the depths of 2-5 mm using a series of probes.…”
Section: Methodsmentioning
confidence: 99%
“…In this regard, a relatively new method of near-field resonance microwave profiling based on the study of tissue dielectric properties, i.e. dielectric permittivity and conductance, attracts special attention [8,[10][11][12][13][14]. This technique has been shown by previous investigations [15][16][17] to be highly informative in dermatology.…”
The aim of the investigation was to study the diagnostic value of the near-field microwave probing in the assessment of the normal and experimentally burned rat skin profiles. Materials and Methods. The investigation was performed on 30 mature Wistar male rats divided into two groups of equal size. The animals of the control group (n=15) did not undergo any manipulations except for a single microwave probing. A contact thermal burn covering 20% of the body area was modeled on the rats of the main group (n=15). Near-field microwave probing was carried out using a device designed in the Institute of Applied Physics of the Russian Academy of Sciences (Nizhny Novgorod, Russia) which enables the estimation of the object dielectric permittivity. A set of probes was used to assess dielectric characteristics of the skin at the depth of 2-5 mm. Results. Real part of dielectric permittivity of the skin and subcutaneous structures in normal rats was determined to rise monotonously with the increase of the probing depth from 2 to 5 mm and a pitch of 0.5 to 1 mm. The tissues of the burn wound demonstrate a higher level of real part of dielectric permittivity relative to the intact skin, the shift having different temporal dynamics. That is immediately after the burn application, changes of the parameter in the superficial biological tissue layers prevail and a day later they prevail in the deeper ones. Conclusion. The method of the resonance microwave investigation can be used to monitor the structure of the skin in norm and in local changes including the depth of thermal tissue injuries.
“…The level of the examined parameter at the minimal and maximal depths differs by 2.55 times (p<0.01) which is determined by the assessment of the deeper structures in the rats performing microwave profiling by the probe working at the depth of 5 mm. It can be also explained by the fact that each subsequent dielectric permittivity value includes the previous one together with the contribution made by the tissues located in the range from the previous to the current probing level [11,[19][20][21].…”
Section: Resultsmentioning
confidence: 99%
“…Near-field microwave probing was carried out using a system, designed in the Institute of Applied Physics of the Russian Academy of Sciences (Nizhny Novgorod, Russia), and specialized software interfacing the system and computer, and enabling the calculation of real part of dielectric permittivity [11,16]. Skin dielectric characteristics were assessed at the depths of 2-5 mm using a series of probes.…”
Section: Methodsmentioning
confidence: 99%
“…In this regard, a relatively new method of near-field resonance microwave profiling based on the study of tissue dielectric properties, i.e. dielectric permittivity and conductance, attracts special attention [8,[10][11][12][13][14]. This technique has been shown by previous investigations [15][16][17] to be highly informative in dermatology.…”
The aim of the investigation was to study the diagnostic value of the near-field microwave probing in the assessment of the normal and experimentally burned rat skin profiles. Materials and Methods. The investigation was performed on 30 mature Wistar male rats divided into two groups of equal size. The animals of the control group (n=15) did not undergo any manipulations except for a single microwave probing. A contact thermal burn covering 20% of the body area was modeled on the rats of the main group (n=15). Near-field microwave probing was carried out using a device designed in the Institute of Applied Physics of the Russian Academy of Sciences (Nizhny Novgorod, Russia) which enables the estimation of the object dielectric permittivity. A set of probes was used to assess dielectric characteristics of the skin at the depth of 2-5 mm. Results. Real part of dielectric permittivity of the skin and subcutaneous structures in normal rats was determined to rise monotonously with the increase of the probing depth from 2 to 5 mm and a pitch of 0.5 to 1 mm. The tissues of the burn wound demonstrate a higher level of real part of dielectric permittivity relative to the intact skin, the shift having different temporal dynamics. That is immediately after the burn application, changes of the parameter in the superficial biological tissue layers prevail and a day later they prevail in the deeper ones. Conclusion. The method of the resonance microwave investigation can be used to monitor the structure of the skin in norm and in local changes including the depth of thermal tissue injuries.
“…На протяжении последних десятилетий ведутся исследования, посвященные СВЧ-диагностике структуры биотканей [8][9][10][11]. Среди неинвазивных методов перспективной считается резонансная ближнепольная СВЧ-томография, которая позволяет изучать пространственное распределение диэлектрической проницаемости и проводимости живых тканей с разрешением значительно меньше длины волны излучения.…”
Section: Introductionunclassified
“…В отличие от пассивного СВЧ-зондирования для проведения ближнепольной томографии требуются значительно меньшие размеры датчика (зонда). При этом разрешающая способность технологии существенно выше [8][9][10][11][12][13][14].…”
г. А.К. Мартусевич, д.б.н., руководитель лаборатории медицинской биофизики Университетской клиники 1 ; С.Ю. Краснова, младший научный сотрудник лаборатории медицинской биофизики Университетской клиники 1 ; С.В. Петров, к.м.н., ведущий научный сотрудник микрохирургического отделения Университетской клиники 1 ; А.Г. Галка, младший научный сотрудник лаборатории медицинской биофизики Университетской клиники 1 ; младший научный сотрудник лаборатории моделирования космической плазмы 2 ; М.S. Petrov, MD, MPH, PhD, Associate Professor, Department of Surgery 3 ; А.В. Новиков, д.м.н., главный научный сотрудник Университетской клиники 1
The aim of the study
was to assess the near-field resonance microwave sounding efficiency to study the dielectric properties of investing tissues in different body areas in healthy rats.
Materials and Methods.
Skin dielectric properties (permittivity and conductivity) were studied in four body parts (medial and lumbar regions of the back, forehead, abdomen) of adult Wistar rats (n=30) using near-field resonance microwave sounding. For measurements, we used a special hardware and software system designed in the Federal Research Center Institute of Applied Physics of the Russian Academy of Sciences.
Results.
Dielectric properties of skin and underlying tissues significantly vary depending on a body area. The medial dorsal region was recorded to have the highest permittivity and conductivity level, while the minimum was found in the abdominal region. Frontal and caudal areas showed intermediate indices. In deepened sounding, dielectric permittivity consistently grows regardless of antenna localization (3 and 5 mm), while the conductivity recedes.
Conclusion.
Near-field resonance microwave sounding enabled to reveal dielectric properties specific for each body area (both by permittivity and conductivity indices and by deep structure of their distribution). The findings should be taken into consideration in topical diagnosis of investing tissues, particularly, when assessing the wound underlying structures, the localization of wound surface boundaries, and the condition of the areas around the wound.
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