Near‐fatal uterine hemorrhage during induction chemotherapy for acute myeloid leukemia: A case report of bilateral uterine artery embolization

Phelan, John T.; Broder, Jonathan; Kouides, Peter A.

doi:10.1002/ajh.20113

Cited by 17 publications

(3 citation statements)

References 40 publications

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“…29,30 Procedures such as uterine artery embolization, endometrial ablation, and hysterectomy are reserved for patients for whom childbearing is complete 31 ; exceptions to this rule are likely to be considered only in life-threatening cases. 32…”

Section: Management Of Platelet Function Disordersmentioning

confidence: 99%

Heavy Menstrual Bleeding as a Common Presenting Symptom of Rare Platelet Disorders: Illustrative Case Examples

Rajpurkar

O’Brien

Haamid

et al. 2016

Journal of Pediatric and Adolescent Gynecology

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Heavy menstrual bleeding (HMB) is a common symptom in patients who present to the obstetrician-gynecologist or adolescent medicine specialist and might result from an underlying inherited bleeding disorder. Whereas relatively common bleeding disorders such as von Willebrand disease are often included in standard laboratory assessments, rarer platelet function disorders can be challenging to diagnose. Additionally, HMB can be a particularly difficult symptom to manage in adolescents with platelet function disorders, and it is associated with decreased quality of life. We review the diagnostic and management issues of patients with platelet function disorders through the presentation of 2 patient case reports, with a focus on a diagnosis of Glanzmann thrombasthenia, an inherited qualitative disorder that affects platelet function. Whereas the first patient presented to the emergency department before the diagnosis of a bleeding disorder and required a hematologic referral and extensive laboratory assessments, the second patient had been diagnosed with Glanzmann thrombasthenia as a child but experienced severe management challenges at the onset of menarche. In both patients, collaboration between the obstetrician-gynecologist or adolescent medicine specialist and the hematologist was critical for achieving acute management of the bleeding symptoms and for ensuring optimal long-term disease management. Together, these cases highlight the importance of properly identifying females with HMB who might have an undiagnosed bleeding disorder and of consulting with a hematologist to determine an appropriate management plan throughout all life stages.

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Section: Management Of Platelet Function Disordersmentioning

confidence: 99%

Heavy Menstrual Bleeding as a Common Presenting Symptom of Rare Platelet Disorders: Illustrative Case Examples

Rajpurkar

O’Brien

Haamid

et al. 2016

Journal of Pediatric and Adolescent Gynecology

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“…Toutefois, certains exposés de cas décrivent l'utilisation de l'embolisation de l'artère utérine aux fins de la maîtrise des saignements utérins abondants attribuables à la chimiothérapie qui ne réagissent pas à la prise en charge médicale. 60,61…”

Section: Considérations Et Options Pour Ce Qui Est De La Suppression unclassified

Suppression menstruelle en présence de circonstances particulières

Kirkham¹,

Ornstein²,

Aggarwal³

et al. 2016

Journal of Obstetrics and Gynaecology Canada

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Suppression menstruelle en présence de circonstances particulières Avis: La présente directive clinique est publiée officiellement dans le Journal d'obstétrique et gynécologie du Canada. Par conséquent, la date de parution pourrait ne pas correspondre à la date de publication originale. Aucune modification n'a été apportée au contenu. La présente directive clinique a été rédigée par le comité canadien d'obstétrique-gynécologie pédiatrique et de l'adolescence (CANPAGO), analysée par le comité consultatif de pratique familiale et approuvée par le comité exécutif et le Conseil de la Société des obstétriciens et gynécologues du Canada.

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“…Although there are very few reports in the literature using this approach for acute heavy uterine bleeding 85 (Class 6), the approach should be considered, at least for women in whom medical management has failed and who may not tolerate surgical therapy, or who require or desire preservation of their uterus. There is evidence that uterine artery embolization may be the most appropriate intervention for women with acute and heavy uterine bleeding secondary to AVM 20 (Class 6).…”

Section: Uterine Artery Occlusionmentioning

confidence: 99%

Acute Uterine Bleeding Unrelated to Pregnancy: A Southern California Permanente Medical Group Practice Guideline

Munro

2013

TPJ

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Acute uterine bleeding unrelated to pregnancy has been defined as bleeding "sufficient in volume as to, in the opinion of the treating clinician, require urgent or emergent intervention." The Southern California Permanente Medical Group updated its guidelines for the management of this condition on the basis of the best available evidence, as identified in a systematic review of the available literature. Given the paucity of studies evaluating this condition, the guidelines, by necessity, include recommendations largely based on opinion or other sources such as case series that are, in general, categorized as low-quality evidence. Medical interventions with single or combined gonadal steroidal agents administered parenterally or orally show promise, but more high-quality studies are needed to better define the appropriate drugs, dose, and administrative scheduling. There is also some evidence that intrauterine tamponade may be useful in at least selected cases. Special attention must be paid to both diagnosing and treating inherited disorders of hemostasis, such as von Willebrand disease, that may otherwise be underdiagnosed in both adolescent and adult women.

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Near‐fatal uterine hemorrhage during induction chemotherapy for acute myeloid leukemia: A case report of bilateral uterine artery embolization

Cited by 17 publications

References 40 publications

Heavy Menstrual Bleeding as a Common Presenting Symptom of Rare Platelet Disorders: Illustrative Case Examples

Heavy Menstrual Bleeding as a Common Presenting Symptom of Rare Platelet Disorders: Illustrative Case Examples

Suppression menstruelle en présence de circonstances particulières

Acute Uterine Bleeding Unrelated to Pregnancy: A Southern California Permanente Medical Group Practice Guideline

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