Nausea and Vomiting in Pregnancy: A Review

Järnfelt-Samsioe, Ann

doi:10.1097/00006254-198707000-00003

Cited by 50 publications

(29 citation statements)

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“…The efferent pathways relay the signals that lead to the coordinated respiratory, gastrointestinal, and abdominal muscle expulsive movements and the accompanying emetic epiphenomena called vomiting. Jarnfelt-Samsoie, Eriksson, Mattsson, and Samsoie (1987) have proposed that hormonal changes in pregnancy due to high levels of circulating steroids, such as estrogen, progesterone, or human chorionic gonadotropin (hCG), may directly stimulate the chemoreceptor cells in the vomiting center (Jarnfelt-Samsoie, 1987).…”

Section: Pathophysiology Of Nausea and Vomitingmentioning

confidence: 99%

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Nausea and Vomiting in Late Pregnancy

Linseth

Vari

2005

Health Care for Women International

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Nausea and vomiting in late pregnancy is a little-studied phenomenon. In this study of 116 midwestern women, 32% of the women had nausea and vomiting after 20 weeks gestation. The purpose of this study was to examine demographic, anthropometric, maternal health factors, and pregnancy outcomes in women who had late nausea and vomiting in pregnancy (NVP) and those that did not. Women who experienced late NVP had significantly higher parity, were older, gained less weight in pregnancy, and slept fewer hours per night than women who did not experience late NVP. By being aware of prenatal factors that may affect nausea and vomiting in late pregnancy, health care providers will be better able to maximize the quality of life for these women.

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Section: Pathophysiology Of Nausea and Vomitingmentioning

confidence: 99%

“…Researchers hypothesize that the prevalence of NVP may be associated with socioeconomic, hereditary, or dietary factors (Jarnfelt-Samsoie, 1987) although the literature found was limited. Nausea and vomiting in pregnancy has been found to be more prevalent in western civilizations.…”

Section: Demographic Maternal Health and Nvpmentioning

confidence: 99%

Nausea and Vomiting in Late Pregnancy

Linseth

Vari

2005

Health Care for Women International

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“…Hyperemesis gravidarum (HG) occurs in 1 to 2% of pregnancies, 1,2 and is the most clinically severe manifestation of nausea and vomiting of pregnancy (NVP). It causes weight loss during pregnancy, [3][4][5][6] dehydration, electrolyte disturbance 7 and nutritional deficiency, which in many cases can necessitate the use of intravenous hydration therapy or parenteral nutrition.…”

Section: Introductionmentioning

confidence: 99%

The psychosocial burden of hyperemesis gravidarum

et al. 2007

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Objective: To describe the psychosocial burden of hyperemesis gravidarum (HG) in a large cohort of affected women, focusing on previously unreported problems. Result: Of the 808 participants, 626 (77.5%) were American. A large majority (82.8%) reported that HG caused negative psychosocial changes, consisting of (1) socioeconomic changes, for example, job loss or difficulties, (2) attitude changes including fear regarding future pregnancies and (3) psychiatric sequelae, for example, feelings of depression and anxiety, which for some continued postpartum. Women who reported that their health-care provider was uncaring or unaware of the severity of their symptoms were nearly twice as likely to report these psychiatric sequelae (odds ratio 1.86, 95% confidence interval 1.06 to 3.29, P ¼ 0.032).Conclusion: Over 80% of a large cohort of women with HG reported that HG caused a negative psychosocial impact.

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“…The cyclical levels of these hormones are higher in pregnant women with nausea or vomiting. 25 Our pregnant women with hypotension also had a higher occurrence of anemia, which may be related to increased risk of bleeding secondary to higher frequencies of hemorrhoids in this group. 26 In Hungary, most anemia during pregnancy is caused by iron deficiency.…”

Section: Discussionmentioning

confidence: 68%

Hypotension in pregnant women: a population-based case–control study of pregnancy complications and birth outcomes

et al. 2010

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Hypotension is frequent in pregnant women; nevertheless, its association with pregnancy complications and birth outcomes has not been investigated. Thus, the aim of this study was to analyze the possible association of hypotension in pregnant women with pregnancy complications and with the risk for preterm birth, low birthweight and different congenital abnormalities (CAs) in the children of these mothers in the population-based data set of the Hungarian Case-Control Surveillance of CAs, 1980CAs, -1996 Prospectively and medically recorded hypotension was evaluated in 537 pregnant women who later had offspring with CAs (case group) and 1268 pregnant women with hypotension who later delivered newborn infants without CAs (control group); controls were matched to sex and birth week of cases (in the year when cases were born), in addition to residence of mothers. Over half of the pregnant women who had chronic hypotension were treated with pholedrine or ephedrine. Maternal hypotension is protective against preeclampsia; however, hypotensive pregnant women were at higher risk for severe nausea or vomiting, threatened abortion (hemorrhage in early pregnancy) and for anemia. There was no clinically important difference in the rate of preterm births and low birthweight newborns in pregnant women with or without hypotension. The comparison of the rate of maternal hypotension in cases with 23 different CAs and their matched controls did not show a higher risk for CAs (adjusted OR with 95% confidence intervals: 0.66, 0.49-0.84). In conclusion, a higher risk for CAs and other adverse birth outcomes was not found in the offspring of pregnant women with hypotension, but maternal hypotension was associated with a higher risk of some pregnancy complications. Keywords: congenital abnormalities; hypotension; hypotension drugs; pregnancy; pregnancy complications INTRODUCTION Hypertension is a common medical condition that has multiple manifestations, including primary and secondary hypertension disease, preeclampsia and gestational hypertension in pregnant women. 1-3 However, the study of the other end of the blood pressure spectrum (that is, hypotension) has been neglected in pregnant women 4 even though hypotension occurs frequently during pregnancy. We were unable to find controlled epidemiological studies regarding the effect of hypotension and related drug treatments for pregnancy complications or adverse birth outcomes in the medical literature. 5 This medical attitude is partially understandable because hypotension is not a disease; rather, it is a symptom of low blood pressure in individuals and is generally not associated with serious complications.Hypotension occurs frequently in Hungarian pregnant women, and obstetricians, in general after consultation with specialists, prefer to treat the more severe and unpleasant symptomatic manifestations of hypotension during pregnancy. However, the potential teratogenic/

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Nausea and Vomiting in Pregnancy: A Review

Cited by 50 publications

References 0 publications

Nausea and Vomiting in Late Pregnancy

Nausea and Vomiting in Late Pregnancy

The psychosocial burden of hyperemesis gravidarum

Hypotension in pregnant women: a population-based case–control study of pregnancy complications and birth outcomes

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