Nausea and vomiting after prostaglandins in day case termination of pregnancy The efficacy of low dose droperidol

Abstract

SummaryThe antiemetic effects of low dose droperidol (O.25

Low-dose droperidol (≤1 mg or ≤15 μg kg−1) for the prevention of postoperative nausea and vomiting in adults

“…Eight trials reported on prevention of early nausea. 19,21,24,26,27,[29][30][31] The tested dose-range was 0.25-0.94 mg. There was no evidence of statistical heterogeneity between study estimates (P ¼ 0.783).…”

“…Significantly fewer patients treated with droperidol were reported to have a headache postoperatively; the NNT point estimate was 24 ( Table 3, Supplemental Digital Content 5, http://links.lww.com/EJA/A26). 1,6,[13][14][15]17,21,22,[24][25][26]30 Significantly more patients receiving droperidol were restless; the number needed to harm was nine ( Table 3, Supplemental Digital Content 6, http:// links.lww.com/EJA/A26). For both outcomes, there was no evidence of dose-responsiveness.…”

Akathisia following low‐dose droperidol for antiemesis in day‐case patients

“…There is a significant difference between the control and droperidol 1 mg groups (p = 0.001). This is important as there is no clear evidence that the antiemetic efficacy of droperidol is dose related; indeed doses as low as 0.25 mg have been shown to be effective [20,21], although droperidol 5 pg.kg ~ ' was not significantly different from placebo [22].…”

Oxygen Saturation during General Anaesthesia and Recovery for Outpatient Oral Surgical Procedures

“…0.004 mg/kg (SO 0.001), was administered intravenously to minimise nausea and vomiting. [20][21][22][23] Oxygen saturation was recorded preoperatively and at thirty seconds intervals after induction for two minutes.…”