Nature's Valuable Resource: Moringa Phytochemicals Targeting TCF7L2 in Drug Design Revealed through MD Simulation and MMGBSA
Amna Saleem,
Hira Mubeen,
Nouman Ali
et al.
Abstract:Diabetes mellitus, a multifactorial disorder, is rapidly evolving into a global epidemic, driven by changes in lifestyle and urbanization. Understanding its genetic underpinnings is essential to developing effective preventive strategies. While genome-wide association studies have identified chromosome 10q25.3 as relevant to type 2 diabetes, the specific causal variations remain elusive. This study focuses on elucidating the role of TCF7L2, a protein implicated in diabetes pathogenesis, through protein network… Show more
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