Natural Terphenyls:  Developments since 1877

Pigments of higher fungi - a review

“…Gilbert, Tapinellaceae) sporophore is leucomentin-2 (34) (Gill & Steglich 1987;Gill 1994;Liu 2006;Hanson 2008b). This The spiromentins possess a unique spiro structure in which a 4,5-dihydroxybenzo-1,2-quinone is linked to a lactone acetal unit (Besl et al 1989).…”

“…Various pigments and other fungi constituents show important biological activities (antioxidative, free radical scavenging, anticarcinogenic, immunomodulatory, antiviral, and antibacterial) that have generated intensive research interest (Steglich 1981;Calìa et al 2003;Liu 2006;Medicinal Mushrooms 2008;Schüffler & Anke 2009).…”

Five new 5,6-seco-tremulane sesquiterpenoids from the basidiomycete Conocybe siliginea

“…Our previous study on the secondary metabolites of the Conocybe siliginea resulted in the isolation of a series of tremulane sesquiterpenoids. [1][2][3] As a part of our efforts to find the structurally diverse and biologically active secondary metabolites from higher fungi, 4-8 a further investigation on C. siliginea has led to the isolation of five new sesquiterpenoids, 11,12-epoxy-10α-hydroxy-5,6-seco-1,6(13)-tremuladien-5,12-olide (1), 11-acetoxy-5,6-seco-1,6(13)-tremuladien-5,12-olide (2), 11-aldehyde-5,6-seco-1,6(13)-tremuladien-5,12-olide (3), 11-acetoxy-10α-hydroxy-5,6-seco-1,6(13)-tremuladien-5,12-olide (4), and 12-acetoxy-5,6-seco-1,6(13)-tremuladien-5,11-olide (5).…”

Two new drimane sesquiterpenoids from cultures of the basidiomycete Trichaptum biforme

“…However, to date, the secondary metabolites of T. biforme have not been investigated further. 2 As a part of our search for diverse secondary metabolites from higher fungi, [6][7][8][9][10][11] we conducted chemical investigations on cultures of T. biforme, which led to the isolation of two new drimane sesquiterpenoids, 11,12-epoxy-3α,6β,9α,11α-tetrahydroxydrimene (1) and 11,12-epoxy-3α,9α,11α-trihydroxydrimene (2), together with four known analogues, danilol (3), 12 isodrimeninol (4), 13,14 3β,11,12-trihydroxydrimene (5), 15,16 and 11,12-dihydroxydrimene (6), 16,17 as well as one chain-shaped sesquiterpenoid, 2,10-dodecadiene-1,6,7-triol (7). 18 Herein, we report the isolation and structural elucidation of 1 and 2.…”