Abstract:Microbes living within the mammalian gastrointestinal tract affect the metabolization and extraction of dietary nutrients; immune function; colonization by pathogens; and risk of autoimmune disease. While most microbiome studies focus on sequences of the 16S gene shared by Bacteria and Archaea, these are not the only regular inhabitants of mammalian guts. Macroparasites such as helminths are nearly ubiquitous in wildlife, and a quarter of the world [prime]s human population harbors helminths; these worms affec… Show more
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