Natural sesquiterpenoids

Abstract

This review covers the isolation, structural determination, synthesis and chemical and microbiological transformations of natural sesquiterpenoids. 421 references are cited.

Linear glandular trichomes of Helianthus (Asteraceae): morphology, localization, metabolite activity and occurrence

“…In Asteraceae, trichome studies focused on capitate glandular trichomes (CGT), which are common in many tribes of the family and are known to produce thousands of STL structures ( Seaman 1982 ; see also reviews by Fraga 1987 , 2011 ), sometimes in combination with flavonoids, acetophenones and other compounds ( Spring 1991 ; Spring et al . 1994 ; Göpfert et al .…”

Structure determination of two new trichothecenes from a halotolerant fungus Myrothecium sp. GS‐17 by NMR spectroscopy

“…[9][10][11] Because the first known member of the trichothecene family, trichothecin, was characterized, to date, more than 200 trichothecenes have been reported. [12,13] These macrolides show a broad range of biological activities, including cytotoxic, [14] antifungal, [15] antimalarial [16] and tyrosinase inhibitory [17] activities.…”

The Transformation of Glaucolide A into Cadinanolides and Hirsutinolides

“…Our results show that both hirsutinolides and cadinanolides can be artifacts produced in the isolation procedure. Such a situation was suggested (16,26) in the transformation of 1 into cadinanolide 3, and in other cases (22)(23)(24)(25), although for 3-oxo-10aH-stilpnomentolide-8-0-(5-acetoxysenecionate) (24), a previously known (13) natural product, this was claimed without stereochemical evaluation.In accordance with these results, utilization of cadinanolideand hirsutinolide-type lactones as taxonomic markers is no longer reasonable. Consequently, the difference between Vernoniinae and non-Vernoniinae taxa, based on the presence of hirsutinolides, may require revision (1).…”