Natural sesquiterpenoids

Synthetic Strategies to Terpene Quinones/Hydroquinones

“…Particularly, the terpenylquinones constitute an interesting group of marine natural product [141,142,143] for which a wide variety of biological activities have been described, including anti-inflamatory, antifungal, anti-HIV and most often antitumor activities [144,145]. …”

“…This has sparked interest in the chemical composition and cytotoxicity of a large number of marine species that contain metabolites with hybrid structures between terpenes and quinones/hydroquinones [76,140,141,146,147,148,149,150]. …”

Four New Chloro-Eremophilane Sesquiterpenes from an Antarctic Deep-Sea Derived Fungus, Penicillium sp. PR19N-1

“…Eremophilane-type sesquiterpenes as a subclass of sesquiterpenoids have gained considerable attentions due to diverse structures and a broad range of biological activities [23,24], most of them distributed in terrestrial plants or microorganisms. To date, more than 900 eremophilane-type sesquiterpenes have been discovered, and to the best of our knowledge, it is the first example that chloro-eremophilane sesquiterpenes were found from microorganisms in the past 30 years.…”

Terpenoids from the Octocorals Menella sp. (Plexauridae) and Lobophytum crassum (Alcyonacea)

“…Octocorals have been proven to be rich sources of natural terpenoid derivatives [1,2] and terpenoid analogues are often found in large amounts in marine invertebrates, and represent the largest percentage of natural products isolated from marine organisms [3]. In a continuation of our search for new substances from marine invertebrates collected off the waters of Taiwan at the intersection of the Kuroshio current and the South China Sea surface current, the chemical constituents of a specimen of gorgonian identified as Menella sp.…”