Natural Rubber Latex Biomaterials in Bone Regenerative Medicine

Kerche, Leandra Ernst; Cavalcante, Dalita Gomes Silva Morais; EloizoJob, Aldo

doi:10.5772/intechopen.69855

Cited by 8 publications

(5 citation statements)

References 59 publications

(65 reference statements)

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“…The biocompatibility of IR was identified in previous researches by culturing L929 mouse fibroblast cell [ 13 ]. The material composed with IR also shows excellent biocompatibility result in the clinical trial [ 14 ]. The high biocompatibility is one of the main reason for us to choose IR as the printing resin.…”

Section: Resultsmentioning

confidence: 99%

Preparation of Biomimetic 3D Gastric Model with Photo-Curing Resin and Evaluation the Growth of Helicobacter pylori

Hsu

Lee

et al. 2021

Polymers

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Three-dimensional (3D) printing technology is now widely used in biomedical developments. Especially, photo-curing systems provide high resolution and precision. The current goal of biomedical 3D printing technology is the printing of human organs, but the current commercial photo-curable materials generally have high mechanical strength that cannot meet the mechanical properties of the object to be printed. In this research, a gastric model was printed using a photo-curing 3D printing technique. To mimic the wrinkle pattern of human gastric tissue, cis-1,4 polyisoprene with different reactive diluents was mixed and identified a formulation that produced a print with human gastric softness. This research discussed the effect of the Young’s modulus of the material and elucidated the relationship between the degree of conversion rate and viscosity. After modifying the cis-1,4 polyisoprene surface from hydrophobic to hydrophilic, we then evaluated its adhesion efficiency for gastric mucin and the gastrointestinal-inhabiting bacterium Helicobacter pylori.

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Section: Resultsmentioning

confidence: 99%

Preparation of Biomimetic 3D Gastric Model with Photo-Curing Resin and Evaluation the Growth of Helicobacter pylori

Hsu

Lee

et al. 2021

Polymers

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“…Information regarding rubber plantations as a source of biomaterial, such as NRL, was provided to the participants, as well as data on relevant and established industries with important socio-economic contributions, both nationally and locally in areas where the sector operates as being the major source of biomaterials with various applications [33,34]. We have also provided information and materials on system approaches relevant to curriculum development [35] to improve the management of agriculture and resources [36], agroecosystem analysis [37], and developmental evaluation (DE) [38].…”

Section: Methodsmentioning

confidence: 99%

Sustaining Biomaterials in Bioeconomy: Roles of Education and Learning in Mekong River Basin

Onpraphai

Jintrawet

Keoboualapha

et al. 2021

Forests

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The demands to improve the livelihood of small farmers require a systemic shift from fossil fuel-based and destructive approaches to sustainable renewable raw materials and non-destructive approaches. This should be accompanied by a fundamental reorganization of education and learning policies to create new bio-oriented value chains for biomaterials, food, wood, and energy, as well as in large parts of the health, manufacturing, and service industries. In the long run, the successful implementation of bio-oriented production depends on the systemic linking of both first- and second-hand learning in communities in rural as well as urban settings. The purpose of this paper is to present a concept for the co-design of a new curriculum to better equip new graduates with the ability to support the effort of the sustainable production of biomaterials that are non-destructive to the environment. To sustain biomaterials and enhance non-destructive ways of thinking, learning needs a community of practice in both online and onsite platforms—allowing students to better understand and support cascade use. Therefore, the use of by-products and recycling products after use will increase in importance. A community of practice, and institutions, must create education and learning platforms for improved actions regarding biomaterials across generations and experiences, which will subsequently be integrated into the circular value chains of the bioeconomy. The first- and second-hand learning to sustain these value chains depends on higher education and learning institutions with both legal mandates and systems approaches.

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“…As latex has been shown to be a biomaterial with strong angiogenic property, it has been commercialized as a bandaid curative (BIOCURE®) in over 60 countries around the world for the treatment of ulcers in diabetic patients (Frade et al, 2004;Kerche-Silva et al, 2018) and also in pressure ulcers (Frade et al, 2006). The latex was proposed as drug delivery system whereby the membrane polymerized at room temperature (27  C) was shown to release 66% of its BSA content for up to 18 days (Herculano et al, 2009).…”

Section: Angiogenesismentioning

confidence: 99%

Therapeutic Potential of Rubber Latex: A Review

Ramarao

Thong

Elumalai

2021

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Exploration of the constituents of rubber for medicinal application is very limited due to the concern of allergenicity. However, the recent discovery of the ability of latex sera to exert specific antiproliferative activity against cancer-origin cell lines has paved a light of utilising rubber latex as therapeutics. Rubber latex and its seed oil show many potentials in various biological activities such as antifungal, antioxidant, anti-melanogenesis as well as a biomaterial in relation to angiogenesis. This review describes the current scientifically reported progress on the potential use of rubber in the field of medical research plus positive side concerning latex allergenicity.

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Natural Rubber Latex Biomaterials in Bone Regenerative Medicine

Cited by 8 publications

References 59 publications

Preparation of Biomimetic 3D Gastric Model with Photo-Curing Resin and Evaluation the Growth of Helicobacter pylori

Preparation of Biomimetic 3D Gastric Model with Photo-Curing Resin and Evaluation the Growth of Helicobacter pylori

Sustaining Biomaterials in Bioeconomy: Roles of Education and Learning in Mekong River Basin

Therapeutic Potential of Rubber Latex: A Review

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