Natural progression of persistent pure ground-glass nodules 10 mm or smaller: long-term observation and risk factor assessment

He, Yifan; Xiong, Ziqi; Tian, Di; Zhang, Jingyu; Chen, Jianzhou; Li, Zhiyong

doi:10.1007/s11604-022-01382-y

Cited by 1 publication

(2 citation statements)

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“…Previous studies have used volumetric measurements to assess the interval growth change in SSNs [ 47 , 48 , 49 , 50 , 51 , 52 , 53 ]. Generally, the nodular volume can be measured in two ways.…”

Section: Relevant Sectionsmentioning

confidence: 99%

“…The main research rationale was that the European position statement recommended lung cancer screening follow up based on semi-automatically measured volume or volume-doubling time assessment of solid nodules ( Figure 7 ) [ 55 ]. Several studies have reported the interval growth of pulmonary SSNs as a growth threshold of 20–30% volumetric increase for growth evaluation [ 47 , 48 , 49 , 50 , 51 , 52 ]. Previous studies have demonstrated that diameter-based assessments may overestimate the actual growth, as compared to growth assessments based on volume-based measurements [ 54 ].…”

Section: Relevant Sectionsmentioning

confidence: 99%

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Managing Persistent Subsolid Nodules in Lung Cancer: Education, Decision Making, and Impact of Interval Growth Patterns

Liu

Liang

et al. 2023

Diagnostics

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With the popularization of lung cancer screening, many persistent subsolid nodules (SSNs) have been identified clinically, especially in Asian non-smokers. However, many studies have found that SSNs exhibit heterogeneous growth trends during long-term follow ups. This article adopted a narrative approach to extensively review the available literature on the topic to explore the definitions, rationale, and clinical application of different interval growths of subsolid pulmonary nodule management and follow-up strategies. The development of SSN growth thresholds with different growth patterns could support clinical decision making with follow-up guidelines to reduce over- and delayed diagnoses. In conclusion, using different SSN growth thresholds could optimize the follow-up management and clinical decision making of SSNs in lung cancer screening programs. This could further reduce the lung cancer mortality rate and potential harm from overdiagnosis and over management.

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