Natural Product Drug Discovery and Analysis Using Mass Spectrometry and Affinity‐Based Technologies

Wang, Evelyn H.; Schug, Kevin A.

doi:10.1002/9781118876015.ch13

Search citation statements

Order By: Relevance

Paper Sections

Select...

Mass Spectrometry1

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2016

Publication Types

Select...

Article1

Relationship

Self Cite1

Independent0

Authors

Journals

Cited by 1 publication

(1 citation statement)

References 117 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In natural product chemistry, the beauty of AS-MS approaches is based on the fact that complex mixtures like herb extracts can be tested at once to isolate and identify drugs or inhibitors with requested affinity for presented targets or target mimics. Many different formats for this type of work-flow exist. , …”

Section: Mass Spectrometrymentioning

confidence: 99%

Structural Analysis of Natural Products

et al. 2016

Self Cite

View full text Add to dashboard Cite

Current mass spectrometry, nuclear magnetic resonance spectroscopy, and X-ray diffraction are presented as structure elucidation tools for analytical chemistry of natural products. Discovering new molecular entities combined with dereplication of known organic compounds represent prerequisites for biological assays and for respective applications as pharmaceuticals or molecular markers. Liquid chromatography is briefly addressed with respect to its use in mass spectrometry- and nuclear magnetic resonance-based metabolomics studies.

show abstract

Section: Mass Spectrometrymentioning

confidence: 99%