Natural polysaccharides as potential anti-fibrotic agents: A review of their progress

Polysaccharides for Medical Technology: Properties and Applications

“…[9] In order to create an optical fiber-based fluorescence biosensor, Wang et al [11] reported applying cholesterol oxidase enzyme to a cellulose acetate membrane that had previously activated by sodium periodate, ethylenediamine, and glutaraldehyde. The development of a novel fiber-optic glucose biosensor employing glucose oxidase enzymes and fluorescent carbon quantum dots immobilized through dip-coating on a cellulose acetate film biosensor was recently reported by Yu et al [12] For the purpose of continuous online monitoring of low glucose concentrations, the suggested optical fiber sensor displayed superior sensitivity and recyclability. Ethyl cellulose membrane, oxazine 170 perchlorate fluorophore, and enzymes immobilized in a matrix of ethyl cellulose membrane and polyurethane hydrogel were used to construct ratiometric fluorescent l-arginine and l-asparagine biosensors reported by An et al [13] The hydrolysis reaction of urea and l-arginine in the presence of urease and arginase as catalysts was the basis for the sensory mechanism.…”

“…[ 7–10 ] It can be employed for health benefits [ 11 ] as well as for support of antifibrotic drug delivery. [ 12 ]…”

“…The development of a novel fiber‐optic glucose biosensor employing glucose oxidase enzymes and fluorescent carbon quantum dots immobilized through dip‐coating on a cellulose acetate film biosensor was recently reported by Yu et al. [ 12 ] For the purpose of continuous online monitoring of low glucose concentrations, the suggested optical fiber sensor displayed superior sensitivity and recyclability. Ethyl cellulose membrane, oxazine 170 perchlorate fluorophore, and enzymes immobilized in a matrix of ethyl cellulose membrane and polyurethane hydrogel were used to construct ratiometric fluorescent l‐arginine and l‐asparagine biosensors reported by An et al.…”

“…[7][8][9][10] It can be employed for health benefits [11] as well as for support of antifibrotic drug delivery. [12] One of the most abundant naturally occurring polysaccharides is cellulose which is found mainly in plants and in some bacteria. It is a linear polymer chain of several hundred to thousands of 𝛽 (1)(2)(3)(4) linked Dglucose.…”

Research progress on the therapeutic effects of polysaccharides on non-alcoholic fatty liver diseases

“…As a major part of natural resources, polysaccharides are captivating growing interest due to their unique advantages, such as low toxicity, high safety, multi-target and multi-pathway. Importantly, polysaccharides have a wide range of pharmacological activities such as anti-inflammatory, antioxidant, anti-fibrotic, immunomodulatory, anti-tumor effects, and so on (6)(7)(8)(9). In terms of NAFLD, some progress has been made recently in the study of anti-NAFLD polysaccharides, and numerous preclinical studies have confirmed that polysaccharides could interfere with the occurrence and development of NAFLD by targeting multiple mechanisms.…”