Abstract:Drugs, having shorter half-life, 10 low oral bio availability, 11 low water solubility, 12 dosing several times a day, undesirable fluctuations in gastric fluids, 13 active locally in the stomach, narrow absorption window in GIT, unstable in the intestinal or colonic environment, disturb normal colonic microbes, exhibit low solubility at high pH values 14 are suitable candidates for formulation of gastro retentive microparticles. NATURAL POLYSACCHARIDES USED FOR THE PREPARATION OF MICROPARTICLES The drug relea… Show more
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