Natural Killer Lymphocytes Mediate Renal Fibrosis Due to Acute Cardiorenal Syndrome
Kevin G. Burfeind,
Yoshio Funahashi,
Adam C. Munhall
et al.
Abstract:Background:
The acute kidney injury (AKI) to chronic kidney disease (CKD) transition presents an opportunity for intervention to prevent CKD. Our lab developed a novel murine model of AKI-CKD transition, cardiac arrest and cardiopulmonary resuscitation (CA/CPR), in which all animals develop CKD at 7 weeks. The purpose of this study was to identify potential immune drivers of fibrosis after CA/CPR.
Methods:
Cardiac arrest was induced by potassium chlorid… Show more
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