Natural killer cells in neuroblastoma: immunological insights and therapeutic perspectives
Magdalena Rados,
Anna Landegger,
Lukas Schmutzler
et al.
Abstract:Natural killer (NK) cells have multifaceted roles within the complex tumor milieu. They are pivotal components of innate immunity and shape the dynamic landscape of tumor-immune cell interactions, and thus can be leveraged for use in therapeutic interventions. NK-based immunotherapies have had remarkable success in hematological malignancies, but these therapies are met with many challenges in solid tumors, including neuroblastoma (NB), a childhood tumor arising from the sympathetic nervous system. With a focu… Show more
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