Natural History, Prognosis, and Socioeconomic Aspects of Psoriatic Arthritis

Helliwell, Philip S.; Ruderman, Eric

doi:10.1016/j.rdc.2015.07.004

Cited by 20 publications

(16 citation statements)

References 48 publications

(43 reference statements)

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“…with great interest . Indeed, early detection of psoriatic arthritis (PsA) in patients with psoriasis is necessary to treat concomitant joint disease adequately, which can significantly impact on quality of life . The Psoriasis Epidemiology Screening Tool (PEST) is a short screening questionnaire that could guide dermatologist decision making, and Coates et al .…”

Section: Evaluation Of the Psoriasis Epidemiology Screening Tool (Pesmentioning

confidence: 99%

“…Indeed, early detection of psoriatic arthritis (PsA) in patients with psoriasis is necessary to treat concomitant joint disease adequately, which can significantly impact on quality of life. 2,3 The Psoriasis Epidemiology Screening Tool (PEST) is a short screening questionnaire that could guide dermatologist decision making, 4,5 and Coates et al have provided evidence that the PEST may be used in both primary and secondary care settings. 1,6 One key finding is that they have questioned the original PEST cut-off score that would warrant rheumatologist referral, with their data now suggesting that a lower cut-off point may be more appropriate.…”

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confidence: 99%

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Screening for psoriatic arthritis using the Psoriasis Epidemiology Screening Tool questionnaire: examining the optimal cut-off

et al. 2017

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Section: Evaluation Of the Psoriasis Epidemiology Screening Tool (Pesmentioning

confidence: 99%

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confidence: 99%

Screening for psoriatic arthritis using the Psoriasis Epidemiology Screening Tool questionnaire: examining the optimal cut-off

et al. 2017

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“…As noted above, PsA is associated with progressive joint damage, reduced quality of life and function, and increased mortality 4 . These untoward outcomes are related to preceding joint inflammation and accrued damage.…”

Section: Importance Of Early Diagnosismentioning

confidence: 89%

“…PsA may result in joint damage leading to marked disability and reduced quality of life. It is associated with increased mortality risk 4 . Progression of joint damage and mortality are related to inflammatory burden as well as previous damage.…”

Section: Introductionmentioning

confidence: 99%

Recent advances in understanding and managing psoriatic arthritis

Gladman

2016

F1000Res

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This article reviews recent advances in psoriatic arthritis (PsA) over the past several years with emphasis on early diagnosis, better understanding of pathogenesis, and new therapeutic approaches. Early diagnosis is important, since people who present late do not fare as well. There are a number of clinical, laboratory, and ultrasound features that can help identify patients destined to develop PsA, and several screening tools have been developed. It is recognized that genetic and epigenetic factors, as well as T cells and cytokines, play a role in the pathogenesis of PsA, and several targets have been identified for therapeutic interventions. New therapies have been developed and tested in PsA and have been found to be highly effective for both skin and joint manifestations of the disease. The expectation is that, in the future, PsA patients will be treated early and more aggressively and that there will not be significant progression of joint damage. Moreover, with effective treatment of the skin and joint disease and management of risk factors for the comorbidities, we can expect to reduce their occurrence and further reduce the excess mortality and reduced quality of life and function in these patients.

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“…Другим аспектом ПсА и псориаза является развитие целого ряда коморбидных заболеваний, в первую очередь сердечно-сосудистых, а также воспалительных заболеваний кишечника, печени, расстройств психики [9][10][11]. Сведения о серьезных сопутствующих заболеваниях при ПсА основаны, главным образом, на данных мировой статистики, их распространенность в российской клинической практике изучена мало.…”

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Optimizing the Diagnosis, a Monitoring and Treatment System for Psoriatic Arthritis in Real Practice: General Principles for Organizing an All-Russian Register of Patients With Psoriatic Arthritis

Коротаева¹,

Корсакова²,

Логинова³

et al. 2019

Naučno-praktičeskaâ revmatologiâ

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The paper presents the design, general characteristics of and possibilities of data usage from the All-Russian register of patients with psoriatic arthritis (PsA).The purpose of creating and introducing the register into Russian healthcare practice is to evaluate the effectiveness of the diagnosis and treatment of PsA. The All-Russian register of PsA patients was created for the period 2016–2018 within the framework of the All-Russian register of patients with arthritis «OREL» on the basis of the V.A. Nasonova Research Institute of Rheumatology and with the support of the All-Russian public organization «Association of Rheumatologists of Russia». This system is an all-Russian population-based register that allows for the recording and monitoring of patients with PsA throughout the follow-up period. This enables healthcare specialists and organizers to obtain reliable information on the state of care for this category of patients in the region.The main purpose of the register is to provide necessary information support and automated technology for solving the problems of accounting, controlling, and monitoring of the status of PsA patients and to organize information interaction between specialists. The register is based on existing state regulatory legal acts. While developing and testing of the register, there were a number of tasks to be solved: to evaluate the efficiency of existing standard and promising targeted PsA therapies in real practice; to assess and improve the routing of patients with PsA. The use of the register allows an operational analysis of the following characteristics: demographic and socioeconomic parameters of patients with PsA; anamnestic data of patients with this condition; results of clinical examinations, instrumental and laboratory data.The geography of the register covers 27 regions of the Russian Federation; the register includes information on 460 patients with PsA.Creating a register permits one to track the dynamics of various parameters (social, demographic, and medical ones), to compare treatment options and the clinical and functional characteristics of patients with PsA, and to evaluate their performance, disability and changes in the social and labor status during the treatment performed. Thus, for the first time in the Russian Federation, the demographic, functional, and socioeconomic parameters of patients with PsA were comprehensively analyzed and the level of performance and impaired daily activities in PsA patients were studied using the WPAI questionnaire; moreover, the patients’ functional and psychological status was evaluated for the first time, by applying the PsAID-12, FACIT questionnaires (in the patients of the V.A. Nasonova Research Institute of Rheumatology).An analysis of the information available in the register makes it possible to compare the efficiency of different PsA treatment regimens, by estimating the rates of remission and/or minimal disease activity in real practice.

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Natural History, Prognosis, and Socioeconomic Aspects of Psoriatic Arthritis

Cited by 20 publications

References 48 publications

Screening for psoriatic arthritis using the Psoriasis Epidemiology Screening Tool questionnaire: examining the optimal cut-off

Screening for psoriatic arthritis using the Psoriasis Epidemiology Screening Tool questionnaire: examining the optimal cut-off

Recent advances in understanding and managing psoriatic arthritis

Optimizing the Diagnosis, a Monitoring and Treatment System for Psoriatic Arthritis in Real Practice: General Principles for Organizing an All-Russian Register of Patients With Psoriatic Arthritis

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