Natural history of medium-sized atrial septal defect in pediatric cases

Abstract

Qp/Qs and RVEDV/LVEDV of medium-sized ASD increase together in childhood. Re-evaluation before adulthood should be considered in patients with no indications of ASD closure in childhood.

Echocardiographic screening for congenital heart disease in 8819 children: A report from local community events for children's healthcare

“…One simple explanation is that we avoid overlap examinations in our cohort. The other possible explanation could be that the some ASD will naturally close before pre-school, and the number may be overestimated [11]. However, in several studies, the wide ranges (4-70%) of spontaneous closure of ASD were reported [12,13].…”

Cardiac MRI right ventricle / left ventricle (RV/LV) volume ratio improves detection of RV enlargement

“…Comparing RV to LV size for RV assessment is not an entirely new concept and has been applied for the assessment of RV size in pediatric patients using angiography . In the PAH population, the RV end‐diastolic dimension and RV end‐diastolic area by echocardiography in the four‐chamber view have been compared to LV and used to identify RV dilation using a normal ratio of 0.5–0.7, and 0.8–1.0, 1.1–1.4, and ≥1.5 as cutoffs for mild, moderate, and severe dilation, respectively .…”

“…13 Comparing RV to LV size for RV assessment is not an entirely new concept and has been applied for the assessment of RV size in pediatric patients using angiography. [14][15][16] In the PAH population, the RV end-diastolic dimension and RV end-diastolic area by echocardiography in the four-chamber view have been compared to LV and used to identify RV dilation using a normal ratio of 0.5-0.7, and 0.8-1.0, 1.1-1.4, and 1.5 as cutoffs for mild, moderate, and severe dilation, respectively. 17 Furthermore, RV/LV end-systolic diameter measured in the parasternal short-axis view by echocardiography correlates well with invasive hemodynamic measurements in children with PH and an RV/LV ratio >1 was associated with adverse outcomes.…”

Pediatric cardiology Spontaneous closure of a large atrial septal defect in an infant

“…Also, Saito et al . [ 6 ] treated an infant with a defect size that enlarged from 9 mm to 27 mm over a period of 9 years. In both cases interventional treatment became unsuitable and finished as surgical closure.…”

“…Atrial septal defect occurs at an incidence rate 1 per 1500 live births, and nowadays the preferred method of treatment is transcatheter closure. Many previous reports regarding natural history of small atrial defects have described spontaneous closure [ 1 – 6 ]. However, large defects usually increase in size with age [ 7 , 8 ].…”