Natural History and Experimental Models

and, Robert H Purcell; Emerson, Suzanne U.

doi:10.1002/9780470987131.ch8

Cited by 6 publications

(1 citation statement)

References 216 publications

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“…Though Hepatitis A is usually a self-limiting disease, atypical manifestations including prolonged and relapsing course are well known. [13][14] Prolonged cholestasis for a period of up to five to seven months with Hepatitis A has been reported. In a series of 108 children with acute viral hepatitis A, 8.3% showed an atypical course, after a short period of progressive enzyme level normalization relapse occurred.…”

Section: Discussionmentioning

confidence: 99%

Hepatitis A Virus Infection Induced Prolonged Cholestasis: A Case Report

Kushwaha

Agrawal

Shukla

2022

JCRAM

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Introduction: Hepatitis A is one of the most common causes of Viral Hepatitis among children. Children have asymptomatic or mild form of disease. Serious manifestation like cholestatic jaundice is very rare in Hepatitis A infection in young children. There have been some reports of manifestations of childhood Hepatitis A occurring in isolation. In this article a young child with Hepatitis A infection who had cholestatic jaundice is reported. The child had flu like symptoms with nausea, vomiting and loss of appetite. Methods: Routine investigations along with LFT (Liver function test) and Hepatitis viral markers were carried out which revealed hyperbilirubinemia suggestive of cholestatic jaundice with Hepatitis A positive. Conclusion: This case illustrates the importance of clinicians having a high clinical suspicion for cholestatic jaundice in patients of Hepatitis A infection.

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Section: Discussionmentioning

confidence: 99%