Natural Fibrous Protein for Advanced Tissue Engineering Applications: Focusing on Silk Fibroin and Keratin

Yang, Yuejiao; Chen, Jie; Migliaresi, Claudio; Motta, Antonella

doi:10.1007/978-981-15-3258-0_3

Cited by 13 publications

(7 citation statements)

References 64 publications

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“…Moreover, it has been used for cell culture and tissue engineered polymer scaffolds (Table 1). It has a wide variety of molecular building, excellent mechanical properties, managing of morphology, and surface modification capabilities make it an absorbing biomaterial for applications in drug delivery, tissue repair, and tissue engineering (Wang et al, 2006;Yang et al, 2020). In addition, silk ease of processing and great biocompatibility has been studied for usage in various tissue engineering applications (Figure 3; Kasoju & Bora, 2012;Kundu et al, 2013).…”

Section: The Role Of Silk In Tissue Engineering and Regenerative Medicinementioning

confidence: 99%

Biomedical applications of silkworm ( Bombyx Mori ) proteins in regenerative medicine (a narrative review)

Khosropanah

Vaghasloo

Shakibaei

et al. 2021

J Tissue Eng Regen Med

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Silk worm (Bombyx Mori) protein, have been considered as potential materials for a variety of advanced engineering and biomedical applications for decades. Recently, silkworm silk has gained significant importance in research attention mainly because of its remarkable and exceptional mechanical properties. Silk has already been shown to have unique interactions with cells in tissues through bio-recognition units. The natural silk contains fibroin and sericin and has been used in various tissues of the human body (skin, bone, nerve, and so on). Besides, silk also still has anti-cancer, anti-tyrosinase, anti-coagulant, anti-oxidant, anti-bacterial, and antidiabetic properties. This article is supposed to describe the diverse biomedical capabilities of B. Mori silk as the appropriate biomaterial among the assorted natural and artificial polymers that are presently accessible, and ideal for usage in regenerative medicine fields.

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Section: The Role Of Silk In Tissue Engineering and Regenerative Medicinementioning

confidence: 99%

Biomedical applications of silkworm ( Bombyx Mori ) proteins in regenerative medicine (a narrative review)

Khosropanah

Vaghasloo

Shakibaei

et al. 2021

J Tissue Eng Regen Med

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“…[277,278] For that, tyrosine residues are modified, increasing almost by 3 the number of available groups (≈5%). [284,285] Diazonium coupling reactions involve an electrophilic aromatic substitution reaction between the tyrosine phenolic (ϕOH) side chains and a diazonium salt (RN 2 + X − ). It results in an azobenzene derivative (Figure 7c).…”

Section: Single Functionalizationmentioning

confidence: 99%

Silk Fibroin as Sustainable Advanced Material: Material Properties and Characteristics, Processing, and Applications

Reizabal

Costa

Pérez‐Álvarez

et al. 2022

Adv Funct Materials

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Biobased resources are proposed as next‐generation materials for advanced application. Among them, silk fibroin, a protein‐based material generally obtained from Bombyx mori cocoons, is considered to play an increasing role in the development of a more sustainable generation of devices. In this review, the silk fibroin molecular structure and its original properties are presented, together with a wide overview of the available modifications and processing methods to reach custom structural and functional variations.

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“…Another variety of novel smart scaffolds are electromechanically active biomaterials. Biomaterials with naturally anisotropic structures such as cellulose [51][52][53] or proteins such as collagen [54,55], silk [56][57][58] and keratin [59,60] are commonly used in tissue engineering. They have also been shown to exhibit electromechanical properties through intrinsic (piezoelectricity, electrostriction and flexoelectricity) and extrinsic processes (electrochemical and electrostatic effects).…”

Section: Smart Scaffoldsmentioning

confidence: 99%

Piezoelectric materials and systems for tissue engineering and implantable energy harvesting devices for biomedical applications

Jarkov

Allan

Bowen

et al. 2021

International Materials Reviews

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Recently, the development of smart materials and the study of their properties has provided an innovative approach to the field of tissue engineering. Piezoelectrics, which are able to generate electric charge in response to mechanical stress or strain have been utilised in the stimulation of electrophysiologically responsive cells , including those found in bone, muscle, and the central and peripheral nervous systems. This area of study has experienced tremendous growth in the past decade in terms of both the array of piezoelectric materials and analytical methods by which they are evaluated in relation to specific tissue types. This review provides a critical and comprehensive overview of the most recent advances in this emerging field. Furthermore, it will extend the scope to examine the most recent developments in piezoelectric biomedical devices that extract energy from physiological processes to either power biomedical implants or act as biomedical sensors .

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Natural Fibrous Protein for Advanced Tissue Engineering Applications: Focusing on Silk Fibroin and Keratin

Cited by 13 publications

References 64 publications

Biomedical applications of silkworm ( Bombyx Mori ) proteins in regenerative medicine (a narrative review)

Biomedical applications of silkworm ( Bombyx Mori ) proteins in regenerative medicine (a narrative review)

Silk Fibroin as Sustainable Advanced Material: Material Properties and Characteristics, Processing, and Applications

Piezoelectric materials and systems for tissue engineering and implantable energy harvesting devices for biomedical applications

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