Natural deep eutectic solvents as tailored and sustainable media for the extraction of five compounds from compound liquorice tablets and their comparison with conventional organic solvents

Abstract

A 1,4-butanediol–levulinic acid system was selected as a topgallant solvent and extraction parameters were optimized. NADES extracts exhibited higher extraction efficiency and in vitro antioxidant activities than conventional solvent extracts.

Optimization of green deep eutectic solvent (DES) extraction of Chenopodium quinoa Willd. husks saponins by response surface methodology and their antioxidant activities

“…The DES extract scavenging rate was higher than the other three extracts, and experiments by Dong showed that this showed a dose relationship with its saponin-containing concentration and indicated that it has some antioxidant capacity and can be used to delay or limit lipid oxidation. 6 …”

“…The DES extract scavenging rate was higher than the other three extracts, and experiments by Dong showed that this showed a dose relationship with its saponincontaining concentration and indicated that it has some antioxidant capacity and can be used to delay or limit lipid oxidation. 6 3.9.2 Analysis of the results of the chelating rate of iron ions. The ability to chelate ferrous ions is one of the commonly used methods to assess the antioxidant activity of a subject.…”

“…4,5 Deep eutectic solvents (DESs) were rst proposed by Abbott in 2003 and are considered green solvents because of their advantages, such as simple synthesis, designable structure and environmental friendliness. 6,7 In recent years, the use of deep eutectic solvents has been reported for the extraction of phenolic compounds in Carthamus tinctorius L., avonoids from Pollen Typhae and polysaccharides from Camellia oleifera Abel. 8 Quinoa saponin is one of the main active substances in quinoa husks, and the common extraction solvents used to extract saponin in the current study are methanol, ethanol, and water.…”

The Most Potent Natural Pharmaceuticals, Cosmetics, and Food Ingredients Isolated from Plants with Deep Eutectic Solvents

“…246−249 The application of organic solvents in the extraction processes comes with some disadvantages, such as high flammability, high vapor pressure, and, in some cases, toxicity. 250,251 Additionally, some extracted compounds, e.g., anthocyanins, are prone to degradation at high temperatures. Thus, it is even more difficult to efficiently extract them with organic solvents.…”

“…Traditional methods of extraction include Soxhlet extraction with solvents such as ethanol, methanol, and acetone and extraction with the aid of stirring and heating, commonly used together with the assistance of ultrasound or microwaves. − The application of organic solvents in the extraction processes comes with some disadvantages, such as high flammability, high vapor pressure, and, in some cases, toxicity. , Additionally, some extracted compounds, e.g., anthocyanins, are prone to degradation at high temperatures. Thus, it is even more difficult to efficiently extract them with organic solvents.…”