Natural course of vitreomacular traction syndrome observed by spectral-domain optical coherence tomography

Zhang, Zhiqiao; Fang, Dong; Zhao, Chan; Dai, Rongping; Wu, Yu; Zheng, Lin; He, Feng; Yang, Zhikun

doi:10.1016/j.jcjo.2014.12.003

Cited by 25 publications

(29 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Observation of VMT may lead to spontaneous separation in 17-34% of eyes, but conversely some may progress to MH, and prolonged disease may result in loss of vision (Almeida et al 2015;Zhang et al 2015). Observation of VMT may lead to spontaneous separation in 17-34% of eyes, but conversely some may progress to MH, and prolonged disease may result in loss of vision (Almeida et al 2015;Zhang et al 2015).…”

Section: Discussionmentioning

confidence: 99%

“…The management of symptomatic VMA does not currently have a gold standard, with options including observation, intravitreal gas, ocriplasmin and PPV. Observation of VMT may lead to spontaneous separation in 17-34% of eyes, but conversely some may progress to MH, and prolonged disease may result in loss of vision (Almeida et al 2015;Zhang et al 2015).…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Intravitreal gas for symptomatic vitreomacular adhesion: a synthesis of the literature

Neffendorf

Simpson

Steel

et al. 2017

Acta Ophthalmologica

View full text Add to dashboard Cite

Symptomatic vitreomacular adhesion (sVMA) is defined as visual loss secondary to foveal damage from vitreomacular traction (VMT) and includes isolated VMT, impending macular hole (MH), and full-thickness MH with persisting vitreous attachment. Management options include pars plana vitrectomy (PPV), intravitreal ocriplasmin, intravitreal gas injection or observation. This synthesis of the literature aimed to assess the safety and efficacy of intravitreal gas for sVMA. Articles describing patients with VMT or MH treated with intravitreal expansile gas were selected by systematic literature review using MEDLINE, EMBASE, and the Cochrane Database of Controlled Trials (CENTRAL) up to September 2016. The main outcomes at 1 month and final review were logarithm of the minimum angle of resolution (logMAR) visual acuity (VA), anatomical success (absence of both VMT and MH, without PPV) and adverse events (AEs). The intended comparator was observation. Nine of 106 identified articles were eligible, and none were randomized controlled trials. The mean VA of 91 eyes improved from 0.55 (Snellen equivalent 6/21) to 0.48 (6/18) logMAR at 1 month and to 0.35 (6/13) logMAR at final review. The mean VA at final review, prior to a vitrectomy, was 0.42 (6/16). Anatomic success was 48% at 1 month and 57% at final review. The reported AEs comprised retinal detachment in two highly myopic eyes. Intravitreal gas injection can relieve sVMA. Larger controlled studies are needed to determine safety and efficacy relative to observation, ocriplasmin, or vitrectomy.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Intravitreal gas for symptomatic vitreomacular adhesion: a synthesis of the literature

Neffendorf

Simpson

Steel

et al. 2017

Acta Ophthalmologica

View full text Add to dashboard Cite

show abstract

“…An OCT-based anatomical classification system for VMI diseases was developed by the International Vitreomacular Traction Study Group. However, while it is exhaustive for anteroposterior traction, it does not provide enough information on tangential traction or on the depth of intraretinal changes, such as iERM stage [29].…”

Section: Introductionmentioning

confidence: 99%

Intraretinal changes in the presence of epiretinal traction

Romano¹,

Cennamo²,

Amoroso³

et al. 2016

Graefes Arch Clin Exp Ophthalmol

View full text Add to dashboard Cite

We found that intraretinal changes were induced by the ERM, and varied according to the depth of traction measured with en face analysis. In the case of traction deeper than 90 μm, we found a significant correlation between the inner area of the epiretinal traction and BCVA. We believe that retinal stress induced by epiretinal traction is better characterized by combining information provided by sagittal and transverse OCT scans, thus defining its prognostic significance in ERM.

show abstract

“…By means of spectral-domain optical coherence tomography (SD-OCT), previous studies investigated the clinical course and the ultrastructural findings of both clinical entities, VMT and ERM, separately, and found not only common characteristics but also differences between them [11,12,13,14,15,16,17,18,19,20,21,22]. It is worthy of note that ERM and VMT often occur together in the same eye; this has already been mentioned [6], but there is no further information regarding the consequences of their potential interrelationship.…”

Section: Introductionmentioning

confidence: 99%

Anatomical and Functional Changes in the Coexistence of Vitreomacular Traction and Epiretinal Membrane: A Spectral-Domain Optical Coherence Tomography Study

Chatziralli

Theodossiadis²,

Datseris³

et al. 2016

Ophthalmic Res

View full text Add to dashboard Cite

Purpose: The purpose of this study was to evaluate the anatomical and functional findings in patients with vitreomacular traction (VMT) combined with epiretinal membrane (ERM) in the same eye. Methods: In this retrospective, cross-sectional study, we studied 65 patients with VMT and ERM. In 36 of them, ERM/VMT had a ‘unified' appearance (group Ι) but in 29, VMT and ERM coexisted without an interrelationship (group ΙΙ). All patients were examined with spectral-domain optical coherence tomography (SD-OCT). We recorded the macular thickness, the presence, type and location of macular edema, the horizontal diameter of VMT, ellipsoid zone/external limiting membrane (EZ/ELM) status, the vitreofoveal angle of VMT nasally and temporally and the best corrected visual acuity (BCVA). Results: Group Ι presented with increased macular thickness, a broader adhesion diameter, extensive EZ/ELM defect and decreased BCVA compared to those where VMT and ERM were not intercorrelated. In group I (‘unified' VMT and ERM), cystoid macular edema was found at a greater percentage (41.7%), while in patients where the 2 entities were not intercorrelated, diffuse macular edema was more evident (69%). There was no statistically significant difference between the 2 groups in the vitreofoveal angle temporally and nasally. Conclusions: Macular thickness, type of macular edema, adhesion diameter, the extent of the EZ/ELM defect and BCVA appeared different in cases where VMT and ERM were unified compared to cases where ERM and VMT coexisted but were not intercorrelated.

show abstract

Natural course of vitreomacular traction syndrome observed by spectral-domain optical coherence tomography

Cited by 25 publications

References 18 publications

Intravitreal gas for symptomatic vitreomacular adhesion: a synthesis of the literature

Intravitreal gas for symptomatic vitreomacular adhesion: a synthesis of the literature

Intraretinal changes in the presence of epiretinal traction

Anatomical and Functional Changes in the Coexistence of Vitreomacular Traction and Epiretinal Membrane: A Spectral-Domain Optical Coherence Tomography Study

Contact Info

Product

Resources

About