Natural course of metastatic castration‐resistant prostate cancer in the era of intensified androgen deprivation therapy in the hormone‐sensitive setting
Georges Gebrael,
Chadi Hage Chehade,
Nicolas Sayegh
et al.
Abstract:BackgroundAndrogen deprivation therapy (ADT) intensification (ADTi) (i.e., ADT with androgen receptor pathway inhibitor or docetaxel, or both) has significantly improved survival outcomes of patients with metastatic hormone‐sensitive prostate cancer (mHSPC). However, the impact of prior ADTi in the mHSPC setting on the disease presentation and survival outcomes in metastatic castration‐resistant prostate cancer (mCRPC) is not well characterized. In this study, our objective was to compare the disease character… Show more
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