“…HIF-1 induces the genes of glucose transporters, enzymes of anaerobic glycolysis, factors and enzymes included in both angiogenesis and metastassis Figure 12. ADM, adrenomedullin; ALDA, aldolase A; ALDC, aldolase C; AMF, autocrine motility factor; CATHD, cathepsin D; c-MET, hepatocyte growth-factor receptor 1; EG-VEGF, endocrine-glandderived VEGF; ENG, endoglin; ENO1, enolase 1; EPO, erythropoietin; ET1, endothelin-1; FN1, fibronectin 1; GLUT1, glucose transporter 1; GLUT3, glucose transporter 3; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; HK1, hexokinase 1; HK2, hexokinase 2; IGF-2, insulin-like growth-factor 2; KRT14, keratin 14; KRT18, keratin 18; KRT19, keratin 19; LDHA, lactate dehydrogenase A; LEP, leptin; MMP2, matrix metalloproteinase 2; NOS2, nitric oxide synthase 2; TGFA, transforming growth-factor a; PFKL, phosphofructokinase L; PFKFB3, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3; PKM, pyruvate kinase M; PGK1, phosphoglycerate kinase 1; TGF-b3, transforming growth-factor b3; TPI, triosephosphate isomerase; UPAR, urokinase plasminogen activator receptor; VEGFR2, VEGF receptor 2; VIM, vimentin [39].…”