Natural co-occurrence of Fusarium toxins in poultry feed and its ingredients

Shar, Zahid Hussain; Shar, H H; Jatoi, A. S.; Sherazi, Syed Tufail Hussain; Mahesar, Sarfaraz Ahmed; Khan, Ezzat; Phanwar, Q. K.

doi:10.1007/s00003-020-01292-z

Cited by 5 publications

(3 citation statements)

References 43 publications

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“…Se ha reportado, que los niveles máximos permitidos dentro de la regulación Europea en alimento terminado para toxina T2 va de los 0.2 a los 2 mg/ kg de alimento terminado (19,20) y se ha establecido como DL50 1 una concentración de 4.97 mg/kg de alimento y 10 mg/ kg como DLPV 2 (18) . Se debe considerar que la toxina T-2 puede generar interacciones en presencia de otras micotoxinas, éstas serán de tipo aditivo en presencia de deoxynivalenol (DON), ocratoxina A (OTA) y fumonisina B1 y de tipo sinérgico en presencia de nivalenol y aflatoxinas (21)(22)(23)(24)(25) .…”

Section: Toxina T-2unclassified

Implicación de las Fusariotoxinas en la producción avícola. Revisión

Gómez Verduzco,

Ávila González,

Téllez Isaías

et al. 2024

Rev. Mex. Cienc. Pecu.

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Las micotoxinas son metabolitos secundarios producidos por hongos de diversos géneros. Dentro de las micotoxinas más importantes se encuentran aquellas producidas por hongos del género Fusarium sp., el cual puede dividirse en varios grupos para su estudio que son el grupo de los tricotecenos (y toxina T-2), de las fumonisinas, principalmente fumonisina B1 (B1, B2, B3, B4, A1 Y A2) y de la zearalenona de efectos estrogénicos. Aunque las fusariotoxinas causan efectos similares debido a que comparten el mismo mecanismo de acción; mediante la alteración de síntesis de proteínas en las aves intoxicadas, es importante mencionar la incidencia, así como las características entre cada una de ellas. Es por esto que en cada apartado se describen las características de cada grupo mencionado.

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Section: Toxina T-2unclassified

Implicación de las Fusariotoxinas en la producción avícola. Revisión

Gómez Verduzco,

Ávila González,

Téllez Isaías

et al. 2024

Rev. Mex. Cienc. Pecu.

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“…However, there is little to no information on the effects of trichothecenes (DON and its active metabolites, and T-2 and its active metabolite, HT-2 toxin) and FB1, particularly not on their effects in combination. As feeds are often contaminated with different mycotoxins [ 18 ], it is critical to understand their collective effects on poultry health.…”

Section: Introductionmentioning

confidence: 99%

The Effects of T-2 Toxin, Deoxynivalenol, and Fumonisin B1 on Oxidative Stress-Related Genes in the Kidneys of Laying Hens

Kövesi,

Kulcsár,

Ancsin

et al. 2024

Toxins

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In the context of nephrotoxic risks associated with environmental contaminants, this study focused on the impact of mycotoxin exposure on the renal health of laying hens, with particular attention to oxidative stress pathways. Sixty laying hens were assigned to three groups—a control group (CON), a low-dose mycotoxin group (LOW), and a high-dose mycotoxin group (HIGH)—and monitored for 72 h. Mycotoxin contamination involved T-2/HT-2 toxin, DON/3-AcDON/15-AcDON, and FB1 at their EU-recommended levels (low mix) and at double doses (high mix). Clinical assessments revealed no signs of toxicity or notable weight changes. Analysis of the glutathione redox system parameters demonstrated that the reduced glutathione content was lower than that in the controls at 48 h and higher at 72 h. Glutathione peroxidase activity increased in response to mycotoxin exposure. In addition, the gene expression patterns of key redox-sensitive pathways, including Keap1-Nrf2-ARE and the AhR pathway, were examined. Notably, gene expression profiles revealed dynamic responses to mycotoxin exposure over time, underscoring the intricate interplay of redox-related mechanisms in the kidney. This study sheds light on the early effects of mycotoxin mixtures on laying hens’ kidneys and their potential for oxidative stress.

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“…Naturally, ground water resources are free from all types of contamination and are in easily access to the public sector but poor human practices such as seepage of waste water from pipelines, discharge of industrial chemicals into water bodies and extensive use of fertilizers on the agricultural land makes the ground water quality objectionable [9]. Moreover, hygienic conditions and depth of bore holes also affect the contamination ratio [10]. Among all toxic pollutants, inorganic chemicals are dominantly present in the ground water resources [11], in which heavy metals are one of them.…”

Section: Introductionmentioning

confidence: 99%

Detection of Hazardous Contaminants in Ground Water Resources: An Alarming Situation for Public Health in Karachi, Pakistan

Razzaq

Zubair

Naz

et al. 2020

Pak J Anal Environ Chem

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Due to industrialization and over population, surface water resources are out of reach from many people so consumption of ground water is the only choice to overcome the water scarcity. Naturally, ground water is one of the significant and potable water resource but some geographical conditions and anthropogenic activities deteriorate the water quality and make it objectionable for drinking. This study was conducted to evaluate the ground water quality of Karachi, Pakistan. For this, 42 ground water samples were collected from different districts of Karachi and analyzed their physicochemical and microbiological characteristics and compared with both international (WHO) and national (SEQS) drinking water standards. Observations of the study declared that overall contamination (physicochemical and microbial) in the ground water samples of different districts of Karachi was as follow West (21%), South (20%), Central (17%), Malir (16%), Korangi (14%) and East (12%). Physical assessment of the study area declared that pH and turbidity of the ground water samples varies in the range of (6.54-7.9) and (0-1.01 NTU) which exist in the standard prescribed limit. Whereas, detection of chemical contaminants particularly TDS (457-12090 mg/L), hardness (118.8-3645 mg/L) and chloride (190-4918 mg/L) content in most of the samples were also exceed from the prescribed limit. Additionally, arsenic was abundantly present ranging from 3.52-13.63 mg/L in all collected samples of Karachi city while the concentration of cadmium (range: 0.0005-0.5012 mg/L) and lead (range: 0.201-1.817 mg/L) were also high in few samples, from the permissible limit of drinking water. Microbial contamination was also detected in which coliforms were present in the range of 0-150 CFU/100mL, which also unfit the water quality. This deteriorated ground water quality of Karachi can be improved by maintenance of proper sanitary conditions of the communities and implementation of water treatments, otherwise consumption of such water may develop serious health related consequences in the consumers.

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Natural co-occurrence of Fusarium toxins in poultry feed and its ingredients

Cited by 5 publications

References 43 publications

Implicación de las Fusariotoxinas en la producción avícola. Revisión

Implicación de las Fusariotoxinas en la producción avícola. Revisión

The Effects of T-2 Toxin, Deoxynivalenol, and Fumonisin B1 on Oxidative Stress-Related Genes in the Kidneys of Laying Hens

Detection of Hazardous Contaminants in Ground Water Resources: An Alarming Situation for Public Health in Karachi, Pakistan

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